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2013
The cerebellar granule cells are the most numerous neurons of the brain. They are also among the most simple by emitting just four short unbranched dendrites innervated by the mossy fibers and a thin axon that branches into the parallel fibers. The granule cells are the only excitatory neurons of the cerebellum and receive inhibition uniquely through ...
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The cerebellar granule cells are the most numerous neurons of the brain. They are also among the most simple by emitting just four short unbranched dendrites innervated by the mossy fibers and a thin axon that branches into the parallel fibers. The granule cells are the only excitatory neurons of the cerebellum and receive inhibition uniquely through ...
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Synaptic Integration in Cerebellar Granule Cells
The Cerebellum, 2008To understand the function of cerebellar granule cells, we need detailed knowledge about the information carried by their afferent mossy fibers and how this information is integrated by the granule cells. Recently, we made whole cell recordings from granule cells in the non-anesthetized, decerebrate cats.
Carl-Fredrik, Ekerot, Henrik, Jörntell
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Cerebellar Granule Cell Migration Involves Proteolysis
1990Histogenesis in the central nervous system requires extensive cell migration. The migration of granule neurons in the neonatal mouse cerebellum has been a focus of study. Although granule cell migration occurs in close association with Bergmann glial fibers1 and Purkinje cell dendrites2, the actual mechanisms of movement that probably involve ...
N W, Seeds +3 more
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Sensory representations in cerebellar granule cells
Current Opinion in Neurobiology, 2009Cerebellar granule cells are an attractive model system for examining synaptic transmission and temporal integration, because of their small number of excitatory synaptic inputs and electrotonic compactness. Recent in vivo whole-cell recordings have revealed how sensory stimuli are represented by synaptic activity across multiple modalities and ...
Alexander, Arenz +2 more
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Anoxic changes in dentate granule cells
Neuroscience Letters, 1989In most of the granule cells recorded, by current clamp and single-electrode voltage-clamp (SEVC), only small depolarizations (or inward currents) and minor conductance increases were observed during brief periods of anoxia (2-3 min). Thus, unlike pyramidal cells, granule cell bodies show little sign of K channel activation by anoxia.
K, Krnjević, Y, Ben-Ari
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Granulated Round Cell Tumor of Cats
Veterinary Pathology, 1993Morphologic and biologic features of five feline granulated round cell tumors were compared with those previously reported to be of globule leukocyte and large granular lymphocyte origin. The five cats ranged from 6 to 9 years of age and presented with nonspecific gastrointestinal signs.
M F, McEntee +3 more
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Lymphocyte granule-mediated cell death
Springer Seminars in Immunopathology, 1998J A, Trapani, D A, Jans, V R, Sutton
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Intrarenal granule-containing cell processes
Journal of the Autonomic Nervous System, 1982D S, Knight, G T, Bazer
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Granule-Mediated Cytolysis of Target Cells
1988The lysis of target cells attacked by cytotoxic T cells appears to be caused by two possibly related phenomena, namely the formation of transmembrane pores in the target cell’s membrane and the cleavage and release of the target cell’s nuclear DNA. At present it is not entirely clear how these effects are mediated at a molecular level.
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