Long-term survival in a patient with leptomeningeal metastases from non-small cell lung cancer treated with stereotactic radiotherapy (SRT), programmed cell death protein 1 (PD-1) inhibitor, and granulocyte-macrophage colony-stimulating factor (GM-CSF): a case report. [PDF]
Huan J, Shan C, Gu H, Li Y, Qi W.
europepmc +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Can serum granulocyte-macrophage colony-stimulating factor and CCL17 levels be a marker of disease activation in spondyloarthritis? [PDF]
Koçak Ulucaköy R +7 more
europepmc +1 more source
Abstract Cancer cachexia, affecting up to 80% of patients with advanced cancer, is characterized by metabolic and inflammatory dysregulation driven by tumour‐ and host‐derived factors. Although cytokines are central to cachexia pathogenesis, their circulating profiles and transcriptional relevance across models and sexes remain incompletely defined. We
Francielly Morena +8 more
wiley +1 more source
Granulocyte-Macrophage Colony-Stimulating Factor in Combination With Chemoradiation for Recurrent or Metastatic Cervical Cancer. [PDF]
Zhang N, Guo MF.
europepmc +1 more source
Abstract The association between higher levels of physical activity and lower cancer risk and mortality is well established. However, a causal link is yet to be proven. Recent studies showed a decrease in the proliferation rates of cultured human cancer cells when the human serum used to stimulate them was conditioned by acute exercise. Here, we tested
Carlos M. Soares +7 more
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Protective effects of engineered Lactobacillus johnsonii expressing bovine granulocyte-macrophage colony-stimulating factor on bovine postpartum endometritis. [PDF]
Guo J +13 more
europepmc +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Elevated Salt or Angiotensin II Levels Induce CD38+ Innate Immune Cells in the Presence of Granulocyte-Macrophage Colony Stimulating Factor. [PDF]
Smith HL +3 more
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Maximal exercise at high altitude does not exacerbate inflammation in the human brain
Abstract figure legend This study investigated arterial–internal jugular venous (IJV) exchange of cytokines in response to low‐intensity and maximal cycling exercise at sea level and following 6–8 days at 3800 m a.s.l. There was a shift towards net release of interleukin‐6 (IL‐6), interleukin‐8 (IL‐8), monocyte chemoattractant protein‐1 (MCP‐1) and ...
Hannah G. Caldwell +11 more
wiley +1 more source

