Results 171 to 180 of about 73,450 (245)

Methotrexate promotes the release of granulocyte-macrophage colony-stimulating factor from rheumatoid arthritis fibroblast-like synoviocytes via autocrine interleukin-1 signaling. [PDF]

Arthritis Res Ther
Bergström B, Selldén T, Bollmann M, Svensson MND, Ekwall AH.   +4 more
europepmc   +1 more source

Advancing Type 1 Diabetes Treatment: 3 PM‐Oriented Innovations in Islet Transplantation and Biomaterial Engineering

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani, Ramin Yaghobi, Mohsen Khosravi Maharlooei, Mehdi Golshan, Mohammad Hossein Karimi   +4 more
wiley   +1 more source

Nocardia Infection in Patients With Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies: A Prospective Multicenter French Study. [PDF]

Open Forum Infect Dis
Kerdiles T, Lejeune S, Portais A, Bourgeois G, Lefevre B, Charmillon A, Sixt T, Moretto F, Cornille C, Vidal M, Coustillères F, Martellosio JP, Quenet M, Belan M, Andry F, Jaffal K, Pinazo-Melia A, Rondeau P, Luque Paz D, Jouneau S, Borie R, Monnier D, Lebeaux D, GM-Noc Study Group .   +23 more
europepmc   +1 more source

Structural Characteristics and Immunoregulatory Effects of Colla Corii Asini Peptides with Iron‐Chelating Capacity

Food Frontiers, Volume 7, Issue 5, September 2026.
Ejiao peptides were fractionated to iron‐chelating F2 (enriched in E‐Xn‐P motif), which restored immune function in CTX‐induced immunosuppressed mice via synergistic regulation of immunity and iron homeostasis. ABSTRACT Iron homeostasis is closely related to immune function, yet the structural basis of food‐derived peptides that modulate this iron ...
Qing‐Tao Zhan, Zi‐Wei Zhao, Jian‐Hang Cai, Xue‐Mei Ge, Shuang‐Di Chen, Xue Tang, Xue‐Ying Ma, Liu‐Ping Fan, Issoufou Amadou, Xiang‐Rong Cheng   +9 more
wiley   +1 more source

Addition of granulocyte macrophage colony stimulating factor (GM-CSF) during in vitro oocyte maturation improves embryo development in a mouse model of advanced maternal age. [PDF]

J Reprod Dev
Saini A, McPherson NO, Nottle MB.
europepmc   +1 more source

Metastatic Testicular Cancer Complicated by Myelodysplastic Syndrome

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction The coexistence of testicular cancer and hematopoietic disorders is rare, and reports on optimal treatment strategies are limited. Here, we present a case of metastatic testicular cancer associated with myelodysplastic syndrome. Case Presentation A 24‐year‐old man with pancytopenia underwent right orchiectomy for a right scrotal ...
Nobuhiko Shimizu, Tomoki Okada, Ryuga Kato, Sosuke Niwa, Takahiro Yanase, Rei Unno, Shoichiro Iwatsuki, Toshiki Etani, Atsushi Okada, Takahiro Yasui   +9 more
wiley   +1 more source

Hypofractionated radiotherapy combined with a PD-1 inhibitor, granulocyte macrophage-colony stimulating factor, and thymosin-α1 in advanced metastatic solid tumors: a multicenter Phase II clinical trial. [PDF]

Cancer Immunol Immunother
Yu J, Yin L, Guo W, Wang Q, Liu J, Zhang L, Ye H, Xia J, Xia Y, Wu J, Wang W, Yang Y, Zong D, He X, Wang L, Jiang H.   +15 more
europepmc   +1 more source

Fibroblast Activation Protein Expression Differs Between Inflamed and Fibrostenotic Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
This study demonstrates that fibroblast activation protein expression is elevated in inflamed and fibrostenotic inflammatory bowel disease, with highest levels in fibrostenotic Crohn's disease. Cellular fibroblast activation protein predominates in inflamed tissues and localises to α‐SMA−PDPN−CD90+ stromal cells. ABSTRACT Background Intestinal fibrosis
Dalia A. Lartey, Bram W. van Os, Bo Jun Ke, Kelly van Wijnbergen, Gert de Hertogh, Luuk J. A. C. Hawinkels, Gianluca Matteoli, Jie Su, Christianne J. Buskens, Jarmilla D. W. van der Bilt, Geert R. A. M. D'Haens, Joep Grootjans, Manon E. Wildenberg, Marieke C. Barnhoorn, Mark Löwenberg   +14 more
wiley   +1 more source

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 250-276, September 2026.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source