Results 141 to 150 of about 189,801 (353)

Single‐cell RNA sequencing reveals the niche transitions in the non‐small cell lung cancer microenvironment mediated by piR‐hsa‐164586 during the invasive and metastatic processes

open access: yesInterdisciplinary Medicine, EarlyView.
A novel mechanism of metastasis of non‐small cell lung cancer (NSCLC) involving piR‐hsa‐164586 was elucidated by single‐cell RNA sequencing. piR‐hsa‐164586 accelerates the invasion and metastasis of NSCLC by activating the PI3K‐AKT pathway and epithelial‐mesenchymal transition.
Yan Tang   +16 more
wiley   +1 more source

Granulocyte colony-stimulating factor and reproductive medicine: A review

open access: yesIranian Journal of Reproductive Medicine, 2015
Background: Recently, the use of granulocyte colony-stimulating factor (G-CSF) has been proposed to improve pregnancy outcomes in reproductive medicine.
Marcelo Borges Cavalcante   +3 more
doaj  

Appropriate administration of Granulocyte-Colony Stimulating Factors

open access: yesReviews in Health Care, 2012
 Chemotherapy-induced febrile neutropenia is a potentially fatal complication of cancer treatment and is also the main reason of dose-reduction and/or delay of chemotherapy regimen. Prophylaxis with G-CSF is applicable to reduce the risk of chemotherapy-induced neutropenia. Two molecules of recombinant G-CSF are available for clinical use: lenograstim,
openaire   +4 more sources

Comprehensive Framework for Oncology Pharmacist‐Led Parenteral Anticancer Therapy Patient Education: The Opinion of the American College of Clinical Pharmacy Hematology/Oncology Practice and Research Network

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
This narrative review summarizes evidence for effective patient education on parenteral anticancer therapies. The authors propose a structured framework for oncology pharmacist‐led patient education on parenteral anticancer therapies that combines pharmacotherapy knowledge and the application of patient‐centered care.
Erin Hickey Zacholski   +7 more
wiley   +1 more source

Recombinant human TNF alpha stimulates production of granulocyte colony- stimulating factor [PDF]

open access: bronze, 1987
HP Koeffler   +5 more
openalex   +1 more source

Intratumoral Nerve Phased Development: A Promising Therapeutic Target

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che   +3 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

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