Granulocyte-macrophage colony-stimulating factor for newly diagnosed glioblastoma [PDF]
Background: There is a clear need to improve the efficiency of therapeutic strategy for patients with newly diagnosed glioblastoma (GBM). The purpose of this study was to evaluate the feasibility of hypofractionated intensity-modulated radiation therapy (
Caineng Cao+12 more
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The nature and action of granulocyte-macrophage colony stimulating factors [PDF]
Abstract Granulocyte-macrophage colony stimulating factor (GM-CSF) stimulates the in vitro proliferation and differentiation of granulocytic and macrophage cells. This regulator is now known to act at other levels of hemopoietic regulation.
AW Burgess, D Metcalf
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We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar+3 more
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Disseminated Cryptococcal Gattii infection in a patient with anti-granulocyte-macrophage colony-stimulating-factor autoantibody: a case report [PDF]
Background Cryptococcosis is an opportunistic fungal infection in immunocompromised patients. The major species include Cryptococcus grubii, Cryptococcus neoformans, and rarely, Cryptococcus gattii.
Chi-Tung Chen+2 more
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Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor [PDF]
Abstract The macrophage-specific colony-stimulating factor (CSF-1, M-CSF) regulates the survival, growth and differentiation of monocytes. We have recently demonstrated that phorbol ester induces expression of CSF- 1 in human monocytes. These findings suggested that activated monocytes are capable of producing their own lineage-specific ...
J Horiguchi, M K Warren, Donald Küfe
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The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors [PDF]
Abstract Rapid progress has occurred recently in characterizing the molecular nature of the specific glycoprotein colony-stimulating factors (CSFs) controlling the proliferation; and some functional activities of granulocytes and monocyte-macrophages.
D Metcalf
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Introduction Cytokines are important immune modulator factors controlling homeostasis of the body and are involved in tissue regeneration after wound healing.
Sławomir Lewicki+8 more
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The human type II collagen (Col II), specifically expressed in chondrocytes, is a crucial component of the adult hyaline cartilage. We examine the potential of artificial induction of Col II in human peripheral blood mononuclear cells (PBMNCs) as a novel
Fu-Hui Wang+8 more
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Immunomodulatory properties of recombinant human granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a myelopoietic growth factor that exerts pleiotropic effect not only on the differentiation of immature progenitor cells into polymorphonuclear neutrophils, monocytes/macrophages and dendritic ...
G. M. Sysoeva+3 more
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G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
There are two types of abnormal hematopoiesis in solid tumor occurrence and treatment: pathological hematopoiesis, and myelosuppression induced by radiotherapy and chemotherapy. In this review we primarily focus on the abnormal pathological hematopoietic
Kai He+5 more
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