Macrophage activation by granulocyte/macrophage colony-stimulating factor. Priming for enhanced release of tumor necrosis factor-alpha and prostaglandin E2. [PDF]
Stefan Heidenreich+4 more
openalex +1 more source
What's New? While melanoma vaccines have shown therapeutic promise, predicting their clinical benefits is challenged by factors such as delayed response to immunotherapy and scarcity of biomarkers. Here, the authors examined the long‐term efficacy of vaccination with either 4 or 12 class I MHC‐restricted peptides in high‐risk melanoma.
Emily K. Ninmer+3 more
wiley +1 more source
Temporal adaptation of neutrophil oxidative responsiveness to n-formyl-methionyl-leucyl-phenylalanine. Acceleration by granulocyte-macrophage colony stimulating factor. [PDF]
English D+5 more
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A case of idiosyncratic drug‐induced agranulocytosis because of sulbactam/ampicillin
We report a case of agranulocytosis caused by sulbactam/ampicillin. During antimicrobial therapy, close monitoring of total white blood cell counts is essential. Abstract Idiosyncratic drug‐induced agranulocytosis is a rare but life‐threatening condition that requires immediate medical intervention.
Kazuya Toda+4 more
wiley +1 more source
Purpose: Granulocyte-macrophage colony-stimulating factor (GM-CSF) cytokine stimulates growth, differentiation, and function of myeloid progenitors. We aimed to study the role of GM-CSF gene expression, its protein, and antibodies in patients with acute ...
Neemat M. Kassem+5 more
doaj +1 more source
Divergent disease patterns in granulocyte-macrophage colony-stimulating factor transgenic mice associated with different transgene insertion sites. [PDF]
D Metcalf, Jeffrey G. Moore
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Abstract Background Coronavirus disease 2019 (COVID‐19) is a complicated disease with widely varying outcomes. Up to 20% of unvaccinated, hospitalized patients infected with COVID‐19 may die during the initial three weeks. Our research shows that COVID‐19 infection results in rapid, remarkable change in the balance between essential fatty acid ...
Vera C. Mazurak+8 more
wiley +1 more source
Advances in prognostic biomarkers for biliary atresia: Current insights and future directions
Abstract Biliary atresia (BA) is a progressive, fibrosing cholangiopathy of infancy characterized by inflammatory obstruction of the bile ducts, ultimately leading to end‐stage liver disease if untreated. Early diagnosis and timely surgical intervention via hepatoportoenterostomy (HPE) are critical for improving outcomes; however, prognostication ...
Ahmad Anouti+6 more
wiley +1 more source
Background: We studied direct effects of human granulocyte-macrophage colony stimulating factor (GM-CSF) on phenotypical characteristics and cytokine-production of non-activated and activated human monocytes/macrophages (Mc/Mphs) and T cells.
Victor Ivanovich Seledtsov+5 more
doaj +1 more source
Effects of granulocyte-macrophage colony-stimulating factor and erythropoietin on leukemic erythroid colony formation in human early erythroblastic leukemias [PDF]
M. T. Mitjavila+9 more
openalex +1 more source