Results 141 to 150 of about 129,342 (334)

Cross‐Analysis of Single‐Cell Transcriptomic Datasets Reveals Conserved Neurogenic Gene Signatures and New Insights Into Neural Stem Cell Aging

open access: yesAging Cell, EarlyView.
Here, we reanalyze single‐cell RNA sequencing datasets demonstrating hippocampal adult neural stem cell (NSC) heterogeneity to resolve classification inconsistencies and identify conserved gene markers. Our findings enhance understanding of NSC dynamics, aging, and senescence, providing a framework for standardized classification and improved insights ...
Oliver Polzer   +4 more
wiley   +1 more source

Cognitive and Psychomotor Processing Speed in Medication‐Naïve Individuals With First‐Episode of Psychosis: The Role of Peripheral Inflammatory Markers

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Hypothesis Deficits in processing speed (PS) and psychomotor speed (PMS) are core cognitive impairments in schizophrenia spectrum disorders, including first‐episode psychosis (FEP). Neuroinflammation has been proposed as a potential contributor to these deficits.
Ángel Yorca‐Ruiz   +8 more
wiley   +1 more source

Pulmonary alveolar proteinosis [PDF]

open access: yesEuropean Respiratory Review, 2011
Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease characterised by alveolar accumulation of surfactant. It may result from mutations in surfactant proteins or granulocyte macrophage-colony stimulating factor (GM-CSF) receptor genes, it may
B. Crestani   +7 more
doaj  

Use of recombinant human granulocyte-macrophage colony-stimulating factor in autologous marrow transplantation for lymphoid malignancies [PDF]

open access: bronze, 1988
John Nemunaitis   +6 more
openalex   +1 more source

Clinical management of CMML—State of the art

open access: yesBritish Journal of Haematology, EarlyView.
Patients with chronic myelomonocytic leukaemia (CMML) typically present with clinical feature including splenomegaly, constitutional symptoms and autoimmune phenomena, as well as with pathological blood counts and biological features in the marrow. These characteristics may influence the assignment to prognostic categories such as the CPSSmol and also ...
K. Nachtkamp   +3 more
wiley   +1 more source

Clonal Hematopoiesis and Solid Cancers

open access: yesCancer Science, EarlyView.
This review explores the relationship between clonal hematopoiesis and solid cancers. Clonal hematopoiesis mutations influence the tumor microenvironment by altering immune regulation, inflammation, and angiogenesis. Understanding these mutations has important clinical implications, including their role in prognosis, treatment response, and potential ...
Yen T. M. Nguyen   +3 more
wiley   +1 more source

Tumor‐Associated Neutrophils Regulate Breast Cancer Progression Through the AQP9/STAT3 Signaling Pathway

open access: yesCancer Science, EarlyView.
Tumor‐associated neutrophils (TANs) enhance STAT3 phosphorylation by upregulating aquaporin 9 (AQP9) to promote breast cancer (BC) progression. AQP9 may be crucial for TAN‐mediated BC progression and is a novel target for immunotherapy in patients with BC.
Wuqin Xu   +5 more
wiley   +1 more source

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