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Granulocyte-Macrophage Colony-Stimulating Factor
Biotherapy, 1990The control of blood cell production is modulated directly or indirectly by more than ten different hematopoietic growth factors (Metcalf 1984). Many names have been assigned to each of the hematopoietic growth factors: although a specific set of names is used throughout this article, the alternative names can be found in other reviews (Nicola and ...
S. Devereux, D. C. Linch
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GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR
Drugs of the Future, 1989Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a well-characterized hematopoietic growth factor. Recently, using purified recombinant-derived material, we have found that GM-CSF is also a potent activator of mature functional macrophages.
H. J. Deeg, H. G. Klingemann
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Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor
New England Journal of Medicine, 1992FOUR colony-stimulating factors influence the survival, proliferation, differentiation, and functional activation of myeloid hematopoietic cells: macrophage colony-stimulating factor (M-CSF), granulocyte colony-stimulating factor (G-CSF), granulocytemacrophage colony-stimulating factor (GM-CSF), and interleukin-3 (formerly known as multi-colony ...
Alastair J.J. Wood +2 more
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Granulocyte-Macrophage Colony-Stimulating Factor in Psoriasis
Dermatology, 1990Granulocyte-macrophage colony-stimulating factor (GM-CSF), a product of activated T lymphocytes, macrophages, endothelial cells, fibroblasts, and keratinocytes, is thought to play an important role in inflammatory reactions by ‘priming’ or enhancing the functions of neutrophils and macrophages.
H. Takematsu, Hachiro Tagami
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Functions of Granulocyte-Macrophage Colony-Stimulating Factor
Critical Reviews in Immunology, 2005GM-CSF was originally defined by its ability to generate in vitro granulocyte and macrophage colonies from bone marrow precursor cells. Apart from its physiological role in the control of alveolar macrophage development, it now appears more likely that its major role lies in its ability to govern the properties of the more mature myeloid cells of the ...
Andrew J. Fleetwood +2 more
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The Granulocyte-Macrophage Colony-Stimulating Factors
Science, 1985The granulocyte-macrophage colony-stimulating factors are well-characterized specific glycoproteins that interact to control the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and monocyte-macrophages.
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European Journal of Cancer, 1994
The purpose of this communication was to explore which situations in radiotherapy might benefit from concomitant administration of haematopoietic growth factors (HGF). Only large-field radiotherapy is likely to induce bone marrow depression, such as irradiation of Hodgkin's disease.
Janssens, P. +3 more
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The purpose of this communication was to explore which situations in radiotherapy might benefit from concomitant administration of haematopoietic growth factors (HGF). Only large-field radiotherapy is likely to induce bone marrow depression, such as irradiation of Hodgkin's disease.
Janssens, P. +3 more
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Current Opinion in Hematology, 1995
Hematopoietic growth factors primarily used in patients with acute myelogenous leukemia after chemotherapy could reduce significantly the neutrophil recovery time in all patients. In high-risk acute myelogenous leukemia, trials also reported a reduction in the incidence of documented infections and early mortality rate.
Gernot Seipelt, Dieter Hoelzer
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Hematopoietic growth factors primarily used in patients with acute myelogenous leukemia after chemotherapy could reduce significantly the neutrophil recovery time in all patients. In high-risk acute myelogenous leukemia, trials also reported a reduction in the incidence of documented infections and early mortality rate.
Gernot Seipelt, Dieter Hoelzer
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Clinical Role of Granulocyte-Macrophage Colony-Stimulating Factor
Hematology/Oncology Clinics of North America, 1989The activity of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) for increasing leukocyte production and enhancing mature neutrophil function has been clearly demonstrated in phase I clinical trials in patients with a variety of hematologic and malignant diseases. The focus of current studies includes determination of optimal
Ronald T. Mitsuyasu, David W. Golde
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Annals of Hematology, 1996
The present study was designed to investigate in vivo immunomodulatory properties of hematopoietic growth factors. The influence on the activation of cytokine synthesis and on the expression of surface antigens associated with cellular activation of G-CSF or GM-CSF was investigated in cancer patients receiving these factors.
U. Haus +9 more
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The present study was designed to investigate in vivo immunomodulatory properties of hematopoietic growth factors. The influence on the activation of cytokine synthesis and on the expression of surface antigens associated with cellular activation of G-CSF or GM-CSF was investigated in cancer patients receiving these factors.
U. Haus +9 more
openaire +3 more sources