Results 21 to 30 of about 129,342 (334)

Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

Journal of the American College of Cardiology, 2005
Two studies in this issue of the Journal report the effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) to promote coronary neovascularization; both were stopped early because of ominous results. In the report by Zbinden et al. ([1][
Robert F. Wilson, Timothy D. Henry
openaire   +2 more sources

Modeling the Hematopoietic Landscape

Frontiers in Cell and Developmental Biology, 2019
Some time ago, we proposed a continuum-like view of the lineages open to hematopoietic stem cells (HSCs); each HSC self-renews or chooses from the spectrum of all end-cell options and can then “merely” differentiate.
Geoffrey Brown, Rhodri Ceredig
doaj   +1 more source

High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

Frontiers in Cell and Developmental Biology, 2021
Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis. Understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies.
Di Cui, Alexandra Franz, Sophie A. Fillon, Linda Jannetti, Timo Isambert, Katrin Fundel-Clemens, Heinrich J. Huber, Coralie Viollet, Alexander Ghanem, Akira Niwa, Bernd Weigle, Stefan Pflanz, Stefan Pflanz   +12 more
doaj   +1 more source

Neutrophils in cancer: neutral no more [PDF]

, 2016
Neutrophils are indispensable antagonists of microbial infection and facilitators of wound healing. In the cancer setting, a newfound appreciation for neutrophils has come into view.
A Blaisdell, A Carus, A Görgens, A Hasenberg, A Kohler, A Mantovani, A Sparmann, A Stoppacciaro, A Swierczak, A Warnatsch, AD Friedman, AD Panopoulos, AJ Casbon, AJ Gentles, AJ Templeton, AK Mankan, AM Houghton, AM Wengner, AP Tittel, AS Chung, B Ruffell, BK Popivanova, BT Suratt, BZ Qian, C Cheretakis, C Gordy, C Martin, CF Wu, CH Ries, CL Semerad, CL Semerad, D Di Mitri, D Marvel, D Metcalf, D Zhang, DI Gabrilovich, DJ Cua, DR Welch, E Elinav, EB Eruslanov, EI Deryugina, EM Bekes, F Chen, F Colotta, F Kuonen, F Liu, F Liu, F Rosenbauer, F Shojaei, F Shojaei, F Shojaei, F Shojaei, G Molineux, G Wang, GJ Guthrie, GJ Lieschke, GO Ahn, H Hirai, H Ji, H Katoh, H Nozawa, H Takahashi, H Tazawa, HH Yan, HK Jensen, HK Kim, HL Rao, HS Deshmukh, I Mishalian, I Petit, J Adolfsson, J Cools-Lartigue, J Crawford, J Jablonska, J Jiao, J Mei, J Pillay, J Pillay, J Pillay, J Sceneay, JC Pahler, JD Spicer, JD Waight, JD Waight, JF Seymour, JI Youn, JI Youn, JL Granick, JL Guerriero, JM Daley, JM Petty, JP Levesque, JT Dancey, JT Erler, JY Sagiv, K Fiedler, K Kersten, K Kim, K Shang, K Shitara, K Tomihara, KA Charles, Karin E. de Visser, KE De Visser, KH Steinbach, KJ Eash, KJ Eash, L Benevides, L Deng, L Gong, L Strauss, L Yang, L Yang, LA Pekarek, LB Rivera, LJ Bayne, LM Coussens, LP Seung, M Bodogai, M Bruchard, M Di Maio, M Elkabets, M Hager, M Ishikawa, M Kowanetz, M Papaspyridonos, M Santoni, M Van Egmond, M Wislez, MA Lopez-Lago, MA Postow, MA Stark, Max D. Wellenstein, MF Denny, MG Manz, MH Kim, MK Richards, MK Srivastava, MP Keane, MT O'Toole, N Antonio, N Borregaard, N Borregaard, P Andreu, P Ehrlich, P Schwarzenberger, P Wu, PC Burdon, PC Vincent, PJ Murray, Q Ma, R Bertini, R Catena, R Noy, RA Caruso, RA Droeser, RN Kaplan, S Acharyya, S Basu, S Dogan, S Hiratsuka, S Tazzyman, S Tazzyman, S Tu, SB Coffelt, SB Coffelt, SB Forlow, Seth B. Coffelt, SH Chang, SH Saverymuttu, SI Rennard, SJ Huh, SJ Moghaddam, SK Bunt, SK Wculek, SL Gaffen, SL Highfill, T Bald, T El Rayes, T Jamieson, T Kitamura, T Lämmermann, T Tak, T Voloshin, T Yamanaka, TE Sutherland, TO Jensen, V Cortez-Retamozo, V Finisguerra, VT Phan, WJ McKinstry, X Qu, X Song, XD Yang, Y Carmi, Y Han, Y Ma, Y Pang, Y Pylayeva-Gupta, Y Sawanobori, Y Tsuda, Y Ueda, Y Ueda, Z Granot, Z Li, ZG Fridlender   +205 more
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Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update. [PDF]

, 2019
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a growth factor that induces the differentiation and proliferation of myeloid progenitors in the bone marrow.
Adorini, Ahn, Alnek, Ananthakrishnan, Aram, Aricha, Basdeo, Bernasconi, Bezbradica, Bhattacharya, Bhattacharya, Bogunovic, Borriello, Campbell, Cao, Casciola-Rosen, Cheatem, Chiewchengchol, Choi, Chuang, Ciric, Codarri, Cook, Cook, Coombes, Croxford, Denson, Derouet, Dieckgraefe, Duhen, Egea, El-Behi, Enzler, Fernandes, Fillatreau, Fraussen, Fuchs, Ganesan, Ganesh, Gangi, Gao, Gathungu, Gaudreau, Ghosh, Gonzalez, Gopisetty, Hansen, Harrington, Hartmann, Hirota, Hirota, Hirota, Huang, Imitola, Jain, Kared, Karni, Kaskow, Katano, Katz, Kelly, Kenkel, King, King, Kister, Lebre, Lee, Lehtonen, Leizer, Li, Li, Li, Li, Makris, Marks, Matsuyama, Mausberg, McWilliams, Meriggioli, Midgley, Mikita, Mufazalov, Muranski, Nagane, Noster, Ortega, Parajuli, Pare, Pare, Park, Piper, Ponomarev, Poppensieker, Ramos-Levi, Rasouli, Reynolds, Roelofs, Rowin, Sakaguchi, Salehi, Samarpita, Scholz, Schutt, Serafini, Shang, Shapouri-Moghaddam, Sheng, Sheng, Sheng, Shiomi, Shiomi, Shiomi, Smith, Srenathan, Stojic-Vukanic, Surendar, Tavakolpour, Touil, Tsark, van de Laar, van Nieuwenhuijze, Vasu, Vincent, Vincent, Vogel, Waisman, Wicks, Wiggins-Dohlvik, Willeke, Xu, Xu, Yang, York, Zhang, Zhao   +134 more
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Distinct macrophage phenotypes skewed by local granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) are associated with tissue destruction and intimal hyperplasia in giant cell arteritis

Clinical & Translational Immunology, 2020
Objective To determine the presence and spatial distribution of different macrophage phenotypes, governed by granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) skewing signals, in giant cell ...
William F Jiemy, Yannick vanSleen, Kornelis SM van derGeest, Hilde A tenBerge, Wayel H Abdulahad, Maria Sandovici, Annemieke MH Boots, Peter Heeringa, Elisabeth Brouwer   +8 more
doaj   +1 more source

Granulocyte-activating mediators (GRAM) [PDF]

, 1988
In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A., Möller, A., Putz, Reinhard, Zeck-Kapp, G.   +3 more
core   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]

Tuberculosis and Respiratory Diseases
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj   +1 more source

Regulation of granulocyte colony-stimulating factor and granulocyte- macrophage colony-stimulating factor expression by oncostatin M [PDF]

Blood, 1993
Oncostatin M (OM) is structurally and functionally related to a subclass of hematopoietic cytokines including leukemia-inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), granulocyte colony- stimulating factor (G-CSF), and interleukin-6 (IL-6).
C Brashem-Stein, Mohammed Shoyab, Jingwen Liu, TJ Brown   +3 more
openaire   +3 more sources