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Granulocyte-Macrophage Colony-Stimulating Factor and Vasculitis
Annals of Internal Medicine, 1989Excerpt To the Editor:Recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) is now being widely used in clinical trials.
Joan H. Schiller +2 more
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The Granulocyte-Macrophage Colony-Stimulating Factors [PDF]
, 1986 Haemopoiesis is the process whereby a small population of multipotential stem cells continuously gives rise to a large number of mature blood cells which comprise eight distinct cellular lineages. In normal health, the circulating levels of mature cells are remarkably invariant, suggesting that their production is tightly regulated.
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Granulocyte Macrophage—Colony Stimulating Factor and Oral Mucositis
Annals of Pharmacotherapy, 2002OBJECTIVE: To evaluate the effect of granulocyte macrophage—colony stimulating factor (GM-CSF) in patients with oral mucositis. DATA SOURCES: Literature was accessed through MEDLINE (1966–June 2000) and bibliographic searches. DATA SYNTHESIS: Published literature assessing the use of GM-CSF to treat or prevent oral mucositis was analyzed.
Stacey M. Fung, Mary J Ferrill
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Colony-Stimulating Factor and the Differentiation of Granulocytes and Macrophages
1977Colony-stimulating factor (GM-CSF), which specifically stimulates mouse bone marrow cells to proliferate and form neutrophil and/or macrophage colonies in semisolid agar cultures (1, 22), has been detected in many biologic fluids (8, 23–26, 30). Most of the sources of GM-CSF are unsuitable for the isolation of this factor and only human urine (30 ...
Antony W. Burgess, Donald Metcalf
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Granulocyte-Macrophage Colony-Stimulating Factor for Cancer Treatment
Oncology, 1994In the 5 years since granulocyte-macrophage colony-stimulating factor (GM-CSF) was first tested clinically, a number of different strategies for its use have been evaluated in patients with malignant disease. These include using GM-CSF to support standard and high-dose chemotherapy, to accelerate myeloid reconstitution following marrow transplantation,
Graham J. Lieschke, Jonathan Cebon
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Effect of surgery on granulocyte/macrophage colony‐stimulating factor
Journal of Surgical Oncology, 1978AbstractEighteen surgical patients were studied to determine the effect of anesthesia (general or spinal) and surgery on serum and urinary colony‐stimulating factor(s) (CSF). CSF is a leukopoietin that stimulates proliferation of macrophages and granulocytes from bone marrow precursor cells.
Roger S. Foster, Howard D. Reines
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Current Opinion in Hematology, 1997
The hematopoietic growth factors granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) not only regulate the numbers of circulating neutrophils but also modulate the function of mature cells. Additionally, newly developed neutrophils subsequently released from the bone marrow in response to colony ...
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The hematopoietic growth factors granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) not only regulate the numbers of circulating neutrophils but also modulate the function of mature cells. Additionally, newly developed neutrophils subsequently released from the bone marrow in response to colony ...
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Cytokine, 2001
In this work we provide evidence showing that granulocytes produce macrophage colony-stimulating factor (M-CSF) from the band cell stage and secrete this factor when induced to differentiate into polymorphonuclear cells by recombinant human granulocyte colony-stimulating factor (rhG-CSF).
Bautista M +8 more
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In this work we provide evidence showing that granulocytes produce macrophage colony-stimulating factor (M-CSF) from the band cell stage and secrete this factor when induced to differentiate into polymorphonuclear cells by recombinant human granulocyte colony-stimulating factor (rhG-CSF).
Bautista M +8 more
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Granulocyte-macrophage colony-stimulating factor and the immune system
Medical Oncology, 1996Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multifunctional cytokine currently used for the reversal of neutropenia associated with cytotoxic chemotherapy, bone marrow and haemopoietic stem cell transplantation. GM-CSF also modulates the function of differentiated white blood cells.
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Granulocyte-macrophage colony-stimulating factor activity in cerebrospinal fluid
Acta Neurologica Scandinavica, 2009The purpose of this study was to analyse the presence of the granulocyte-macrophage colony-stimulating factor (GM-CSF) in human cerebrospinal fluid (SF) of patients affected by multiple sclerosis (MS) in comparison with non-inflammatory neurological diseases.All SFs were collected from 59 patients for diagnostic purpose.
LEONARDI A. +9 more
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