Results 291 to 300 of about 134,623 (343)

Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu   +4 more
wiley   +1 more source

Integrative Single‐Cell Analysis Reveals Targetable Vacuole Membrane Protein 1‐Mediated Mechanism of Tumor Angiogenesis in Glioblastoma

open access: yesMedComm, Volume 7, Issue 2, February 2026.
VMP1 promotes angiogenesis in glioblastoma (GBM) through VEGFA‐VEGFR2 signaling and activation of endothelial cells. The FDA‐approved anti‐VEGFA antibody, bevacizumab (BEV), can counteract VMP1's tumor‐promoting effect in GBM. Targeting VMP1 or its associated pathways could be a new therapeutic strategy, either alone or in combination with BEV.
Lei Jin   +8 more
wiley   +1 more source

Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Shriya Makam, Hana M. Dobrovolny
wiley   +1 more source

Granulocyte-Macrophage Colony-stimulating Factor

Biotherapy, 1990
Publisher Summary Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of the four classical colony-stimulating factors discovered in the 1960s following the introduction of semi-solid bone-marrow culture techniques. The human GM-CSF gene is located on chromosome 5 (q25–q31) within 10 kb of the interleukin-3 (IL-3) gene and in the same ...
S, Devereux, D C, Linch
  +5 more sources

Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

New England Journal of Medicine, 1992
FOUR colony-stimulating factors influence the survival, proliferation, differentiation, and functional activation of myeloid hematopoietic cells: macrophage colony-stimulating factor (M-CSF), granulocyte colony-stimulating factor (G-CSF), granulocytemacrophage colony-stimulating factor (GM-CSF), and interleukin-3 (formerly known as multi-colony ...
Alastair J.J. Wood   +2 more
openaire   +1 more source

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