Results 61 to 70 of about 134,623 (343)

In-silico analysis of myeloid cells across the animal kingdom reveals neutrophil evolution by colony-stimulating factors

eLife, 2020
Neutrophils constitute the largest population of phagocytic granulocytes in the blood of mammals. The development and function of neutrophils and monocytes is primarily governed by the granulocyte colony-stimulating factor receptor family (CSF3R/CSF3 ...
Damilola Pinheiro, Marie-Anne Mawhin, Maria Prendecki, Kevin J Woollard   +3 more
doaj   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells [PDF]

, 2011
The molecular mechanism between atherosclerosis formation and periodontal pathogens is not clear although positive correlation between periodontal infections and cardiovascular diseases has been reported.
de Winther, Demmer, Diya, Fischer, Gamble, Ghosh, Giacona, Gibson, Gitlin, Groeneweg, Janabi, Kleemann, Lalla, Li, Lu, Ma, Majdalawieh, Martin, Mikita, Oram, Qi, Robbesyn, Ross, Zhou   +23 more
core   +2 more sources

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

IFN-gamma is associated with risk of Schistosoma japonicum infection in China.

, 2003
Before the start of the schistosomiasis transmission season, 129 villagers resident on a Schistosoma japonicum-endemic island in Poyang Lake, Jiangxi Province, 64 of whom were stool-positive for S.
Bickle, QD, Chen, SZ, Cousens, SN, Hu, LS, Ji, MJ, Shen, L, Su, C, Taylor, MG, Weir, RE, Wu, GL, Wu, HW, Xie, ZW, Zhang, Y, Zhang, ZS   +13 more
core   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update. [PDF]

, 2019
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a growth factor that induces the differentiation and proliferation of myeloid progenitors in the bone marrow.
Adorini, Ahn, Alnek, Ananthakrishnan, Aram, Aricha, Basdeo, Bernasconi, Bezbradica, Bhattacharya, Bhattacharya, Bogunovic, Borriello, Campbell, Cao, Casciola-Rosen, Cheatem, Chiewchengchol, Choi, Chuang, Ciric, Codarri, Cook, Cook, Coombes, Croxford, Denson, Derouet, Dieckgraefe, Duhen, Egea, El-Behi, Enzler, Fernandes, Fillatreau, Fraussen, Fuchs, Ganesan, Ganesh, Gangi, Gao, Gathungu, Gaudreau, Ghosh, Gonzalez, Gopisetty, Hansen, Harrington, Hartmann, Hirota, Hirota, Hirota, Huang, Imitola, Jain, Kared, Karni, Kaskow, Katano, Katz, Kelly, Kenkel, King, King, Kister, Lebre, Lee, Lehtonen, Leizer, Li, Li, Li, Li, Makris, Marks, Matsuyama, Mausberg, McWilliams, Meriggioli, Midgley, Mikita, Mufazalov, Muranski, Nagane, Noster, Ortega, Parajuli, Pare, Pare, Park, Piper, Ponomarev, Poppensieker, Ramos-Levi, Rasouli, Reynolds, Roelofs, Rowin, Sakaguchi, Salehi, Samarpita, Scholz, Schutt, Serafini, Shang, Shapouri-Moghaddam, Sheng, Sheng, Sheng, Shiomi, Shiomi, Shiomi, Smith, Srenathan, Stojic-Vukanic, Surendar, Tavakolpour, Touil, Tsark, van de Laar, van Nieuwenhuijze, Vasu, Vincent, Vincent, Vogel, Waisman, Wicks, Wiggins-Dohlvik, Willeke, Xu, Xu, Yang, York, Zhang, Zhao   +134 more
core   +2 more sources

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Granulocyte-Macrophage Colony-Stimulating Factor Production and Tissue Eosinophilia in Chronic Rhinitis

International Archives of Otorhinolaryngology, 2016
Introduction Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a strong proinflammatory cytokine that takes part in allergic nasal inflammation as an eosinophil colony-stimulating factor.
Aleksandar Peric, Cveta Spadijer-Mirkovic, Svjetlana Matkovic-Jozin, Ljiljana Jovancevic, Danilo Vojvodic   +4 more
doaj   +1 more source

Aberrant expression of proatherogenic cytokines and growth factors in human umbilical vein endothelial cells from newborns of type 2 diabetic women

SAGE Open Medicine, 2021
Objectives: This study reports the levels of cytokines, chemokines, and growth factors previously identified as taking part in the pathology of atherosclerosis in human umbilical vein endothelial cells derived from mothers with type 2 diabetes and ...
Samar Sultan
doaj   +1 more source