Results 101 to 110 of about 106,660 (298)

Inhibition of platelet aggregation by granulocytes stimulated during experimental trauma

, 1990
The effect of granulocytes, stimulated in vivo by standardized soft tissue trauma, on the aggregation of autologous platelets in vitro, was studied in the pig.
Thorne, J., Thorne, J.,, Faldt, R., Faldt, R.,, Zoucas, E.,, Ankerst, J.,, Lund University., Zoucas, E., Ankerst, J.   +8 more
core   +1 more source

PFOS > 90th percentile, no granulocytes, boys, girls, all

, 2023
PFOS > 90th percentile, no granulocytes, boys, girls ...
Chongjing Gao (10099447), Weihua Guan (345071), Edwina Yeung (8468436), Chathura J. Gunasekara (9048255), Robert A. Waterland (10099444), Erin M. Bell (517092), Sonia Robinson (9981323), Rajeshwari Sundaram (3234090), Xuehuo Zeng (7274687), Pauline Mendola (71729), Diane L. Putnick (10099441), Kurunthachalam Kannan (487986)   +11 more
core   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Image of immunologically activated granulocytes, including phagocytosis and nodulation.

, 2015
(A, B, and C) The granulocytes changed their shape and generated lodopodia-like or fan-like structures (indicated by white arrow). The vacuoles expanded in the cytoplasm (indicated by red arrows). Several filopodia were also generated in plasmatocytes (D;
Saeyoull Cho (607394), Sejung Hwang (748233), Jiae Lee (23250), Kyeongrin Bang (607393)   +3 more
core   +1 more source

Dordaviprone Maintenance After Allogeneic HCT for High‐Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm

American Journal of Hematology, EarlyView.
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt, Christopher S. Wichman, Alyssa Bouska, Moataz Ellithi, Michael Haddadin, Javeed Iqbal, James E. Talmadge, Lori J. Maness, Krishna Gundabolu   +8 more
wiley   +1 more source

Editorial: Emerging Roles for Type 2-Associated Cells and Cytokines in Cancer Immunity

Frontiers in Immunology, 2021
Giovanna Schiavoni, Ariel Munitz, Jessica Strid   +2 more
doaj   +1 more source

Single‐center off‐label benralizumab use for refractory hypereosinophilic syndrome demonstrates satisfactory safety and efficacy

eJHaem
Introduction Benralizumab is an interleukin 5‐receptor‐blocking drug registered for the treatment of eosinophilic asthma. It has proven efficient and safe in a small phase‐II trial in hypereosinophilic syndrome and is currently being investigated in a ...
Yvonne Veltman, Anna M. Aalbers, Maud A. W. Hermans, Pim G. N. J. Mutsaers   +3 more
doaj   +1 more source

The impact of pre-analytical treatment and sorting on human neutrophil function

Veterinární Medicína, 2014
This study was designed to test the hypothesis that pre-analytical treatment of relatively fragile cells is more important for their viability and function than shear forces and decompression shocks on a flow cytometric sorter.
L. Hromadkova, L. Zarybnicka, J. Vavrova, Z. Bilkova, Z. Sinkorova   +4 more
doaj   +1 more source

Granulocytes as modulators of dendritic cell function

, 2017
Effector T cell development is directly driven by APCs, in particular, by antigen-primed dendritic cells (DCs). Depending on the pathogenic stimulus and the microenvironment, DCs induce proliferation and polarization of naive CD4(+) T cells into ...
de Jong, Esther C., Breedveld, Annelot, Marjolein van Egmond, van Egmond, Marjolein, Tom Groot Kormelink, Esther C. de Jong, Groot Kormelink, Tom, Kormelink, Tom Groot, Annelot Breedveld   +8 more
core   +1 more source

High Proportion of PNH Type II Neutrophils Is Associated With Thrombosis in Patients Displaying a PNH Clone ≥ 1%

American Journal of Hematology, EarlyView.
ABSTRACT The clinical significance of PNH Type II white blood cells (WBCs) remains unclear. We assessed the relative percentage (rel%) of Type II neutrophils in 355 patients with a PNH clone ≥ 1% on neutrophils enrolled by 33 flow cytometry laboratories in the 5‐year French nation‐wide multicenter prospective observational study.
Orianne Wagner‐Ballon, Anne‐Catherine Lhoumeau, Anna Raimbault, Camille Debord, Jean‐Philippe Vial, Valérie Soenen, Mélanie Pannetier, Edouard Bonneville, Elsa Bera, Caroline Bret, Nicolas Chapuis, Véronique Latger‐Cannard, Caroline Mayeur‐Rousse, Véronique Harrivel, François Vergez, Marie Loosveld, Juliette Vo Xuan, Stéphanie Mathis, Gérard Socié, Flore Sicre de Fontbrune, Régis Peffault de Latour, Bernard Drenou, Agathe Debliquis, Magali Le Garff‐Tavernier, on behalf of the French PNH working group CytHem‐HPN, Thomas Boyer, Mikaël Roussel, Marie Guillon, Sabrina Bouyer, Isabelle Kittler, Franck Geneviève, Julien Guy, Sophie Brun, Claude Capron, Sébastien Lachot, Francine Garnache‐Ottou, Richard Veyrat‐Masson, Corine Brunet, Caren Brumpt, Ludovic Lhermitte. Finally, Louis Terriou, Nicolas Blin   +41 more
wiley   +1 more source