In the Thick of It: Formation of the Tuberculous Granuloma and Its Effects on Host and Therapeutic Responses [PDF]
Frontiers in Immunology, 2022The defining pathology of tuberculosis is the granuloma, an organized structure derived from host immune cells that surrounds infecting Mycobacterium tuberculosis.
Mark R. Cronan
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Association between the COVID-19 pandemic and granuloma formation following lower blepharoplasty [PDF]
American Journal of Ophthalmology Case ReportsPurpose: We hypothesize that lower blepharoplasty post-operative granuloma formation increased during the COVID-19 pandemic. Observations: Retrospective consecutive case series of first-time lower blepharoplasties performed at an academic private ...
Shane Griffin+2 more
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An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2
Nature Communications, 2023Granulomas often form around pathogens that cause chronic infections. Here, we discover an innate granuloma model in mice with an environmental bacterium called Chromobacterium violaceum.
Carissa K. Harvest+14 more
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Laser Assisted Management of Telangiectatic Granuloma in Third Trimester of Pregnancy – A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2018Telangiectatic granuloma is an uncommon overgrowth of the tissues that occurs as a result of various stimuli such as low grade local irritation, traumatic injury or hormonal factors.
Aparna Venkatasubramanyam+4 more
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Oral pyogenic granuloma: A case report and review of literature [PDF]
Acta Stomatologica Naissi, 2022Uvod: Pyogenic granuloma is a common non neoplastic growth in the oral cavity which is hyperplastic in nature. Various theories of etiopathogenesis have been suggested for pyogenic granuloma.
Achalli Sonika, Patia Murali
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Granuloma annulare (GA) is a benign granulomatous skin disease. Subcutaneous granuloma annulare is a rare variant in adults, predominantly affects women and typically involves hands.
L. Ruiz+4 more
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Spatial Transcriptomics Reveals Signatures of Histopathological Changes in Muscular Sarcoidosis
Cells, 2023Sarcoidosis is a multisystemic disease characterized by non-caseating granuloma infiltrating various organs. The form with symptomatic muscular involvement is called muscular sarcoidosis. The impact of immune cells composing the granuloma on the skeletal
Hippolyte Lequain+7 more
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The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation
European Respiratory Journal, 2020Sarcoidosis is a disease characterised by granuloma formation. There is an unmet need for new treatment strategies beyond corticosteroids. The NLRP3 inflammasome pathway is expressed in innate immune cells and senses danger signals to elicit inflammatory
C. Huppertz+9 more
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Schistosoma mansoni Eggs Modulate the Timing of Granuloma Formation to Promote Transmission
bioRxiv, 2020Schistosome eggs provoke the formation of granulomas, organized immune aggregates, around them. For the host, the granulomatous response can be both protective and pathological.
Kevin K. Takaki+4 more
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