Results 11 to 20 of about 168,174 (295)

In the Thick of It: Formation of the Tuberculous Granuloma and Its Effects on Host and Therapeutic Responses

Frontiers in Immunology, 2022
The defining pathology of tuberculosis is the granuloma, an organized structure derived from host immune cells that surrounds infecting Mycobacterium tuberculosis.
Mark R. Cronan
doaj   +2 more sources

VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection

Cell Reports, 2019
Summary: Many autoimmune and infectious diseases are characterized by the formation of granulomas which are inflammatory lesions that consist of spatially organized immune cells.
Jeffrey S. Harding, Melinda Herbath, Yuli Chen, Aditya Rayasam, Anna Ritter, Balazs Csoka, George Hasko, Iacovos P. Michael, Zsuzsanna Fabry, Andras Nagy, Matyas Sandor   +10 more
doaj   +2 more sources

Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation

Immunity, 2023
Summary Granulomas are lumps of immune cells that can form in various organs. Most granulomas appear unstructured, yet they have some resemblance to lymphoid organs.
Thomas Krausgruber, A. Redl, D. Barreca, K. Doberer, Daria Romanovskaia, Lina Dobnikar, Maria Guarini, L. Unterluggauer, L. Kleissl, D. Atzmüller, C. Mayerhofer, Aglaja Kopf, S. Saluzzo, Clarice X. Lim, Praveen Rexie, T. Weichhart, C. Bock, G. Stary   +17 more
semanticscholar   +1 more source

The Tuberculous Granuloma and Preexisting Immunity.

Annual Review of Immunology, 2022
Pulmonary granulomas are widely considered the epicenters of the immune response to Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Recent animal studies have revealed factors that either promote or restrict TB immunity within
Sara B. Cohen, B. Gern, K. Urdahl
semanticscholar   +1 more source

An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2

Nature Communications, 2023
Granulomas often form around pathogens that cause chronic infections. Here, we discover an innate granuloma model in mice with an environmental bacterium called Chromobacterium violaceum.
Carissa K. Harvest, Taylor J. Abele, Chen Yu, Cole J. Beatty, Megan E. Amason, Zachary P. Billman, Morgan A. DePrizio, Fernando W. Souza, Carolyn A. Lacey, Vivien I. Maltez, Heather N. Larson, Benjamin D. McGlaughon, Daniel R. Saban, Stephanie A. Montgomery, Edward A. Miao   +14 more
doaj   +1 more source

A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization.

Cell, 2021
The central pathogen-immune interface in tuberculosis is the granuloma, a complex host immune structure that dictates infection trajectory and physiology.
M. Cronan, E. Hughes, W. J. Brewer, Gopinath Viswanathan, E. G. Hunt, Bindu Singh, S. Mehra, Stefan H. Oehlers, S. Gregory, D. Kaushal, D. M. Tobin   +10 more
semanticscholar   +1 more source

Incidence and Prevalence of Granuloma Annulare in the United States.

JAMA dermatology, 2021
Importance Although several single-center studies have estimated that granuloma annulare may account for approximately 0.1% to 0.4% of new patients presenting to dermatologists, large-scale population-based studies estimating the prevalence and incidence
J. Barbieri, O. Rodriguez, M. Rosenbach, D. Margolis   +3 more
semanticscholar   +1 more source

Laser Assisted Management of Telangiectatic Granuloma in Third Trimester of Pregnancy – A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2018
Telangiectatic granuloma is an uncommon overgrowth of the tissues that occurs as a result of various stimuli such as low grade local irritation, traumatic injury or hormonal factors.
Aparna Venkatasubramanyam, Rashmi Hegde, Shradha Sigtia, Sangeeta Muglikar, Varsha Shourie   +4 more
doaj   +1 more source

Oral pyogenic granuloma: A case report and review of literature [PDF]

Acta Stomatologica Naissi, 2022
Uvod: Pyogenic granuloma is a common non neoplastic growth in the oral cavity which is hyperplastic in nature. Various theories of etiopathogenesis have been suggested for pyogenic granuloma.
Achalli Sonika, Patia Murali
doaj   +1 more source

Detection rates of non-cavitary epithelioid cell granuloma by gastrointestinal biopsy in patients with treatment-naïve Crohn's disease

Inflammatory Intestinal Diseases, 2023
Introduction: Detecting non-cavitary epithelioid cell granuloma by gastrointestinal biopsy is important in the initial diagnosis of Crohn’s disease (CD).
Katsuya Endo, Yoko Kawakami, Yuki Yoshino, Shiho Kondo, Daisuke Fukushi, Atsuko Takasu, Takayuki Kogure, Morihisa Hirota, Kazuhiro Murakami, Kennichi Satoh   +9 more
doaj   +1 more source