Results 31 to 40 of about 247,296 (388)

Assessment of Experimental Techniques That Facilitate Human Granuloma Formation in an In Vitro System: A Systematic Review

open access: yesCells, 2022
The process of granuloma formation is complex, and due to species differences, the validity of animal studies is somewhat questioned. Moreover, the large number of animals needed to observe the different stages of development also raises ethical ...
Nirosha Ganesan   +3 more
doaj   +1 more source

Clinical management of a peri-implant giant cell granuloma [PDF]

open access: yes, 2015
Purpose. Implant therapy plays an important role in contemporary dentistry with high rates of long-term success. However, in recent years, the incidence of peri-implantitis and implant failures has significantly increased.
Carbone, D.   +4 more
core   +4 more sources

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

open access: yes, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams   +117 more
core   +1 more source

Endoscopic endonasal management of recurrent petrous apex cholesterol granuloma. [PDF]

open access: yes, 2011
Petrous apex cholesterol granulomas (PACG) are uncommon lesions. Recurrence following transcranial or endonasal approaches to aerate the cyst occurs in up to 60% of cases. We describe the technical nuances pertinent to the endonasal endoscopic management
Carrau, Ricardo L   +5 more
core   +1 more source

Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma

open access: yesNature Communications, 2019
Granulomas are the pathological hallmark of tuberculosis (TB) and the niche where bacilli can grow and disseminate or the immunological microenvironment in which host cells interact to prevent bacterial dissemination.
B. Carow   +5 more
semanticscholar   +1 more source

Infiltrated papules on the trunk and headaches: A case of actinic granuloma and a review of the literature

open access: yesInternational Journal of Women's Dermatology, 2015
Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomitant
Sonal A. Parikh, BS   +5 more
doaj   +1 more source

Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery [PDF]

open access: yes, 2016
Purpose: The purpose of this study was to compare inflammatory events and graft characteristics 1 month and 6 months after conjunctival limbal autograft (CLAU) with and without intraoperative mitomycin C (MMC).
Asaad Ammaar, Mouafk   +4 more
core   +2 more sources

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]

open access: yes, 2007
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner   +7 more
core   +3 more sources

IL‐13‐regulated Macrophage Polarization during Granuloma Formation in an In Vitro Human Sarcoidosis Model

open access: yesAmerican Journal of Respiratory Cell and Molecular Biology, 2019
The mechanisms underlying abnormal granuloma formation in patients with sarcoidosis are complex and remain poorly understood. A novel in vitro human granuloma model was used to determine the molecular mechanisms of granuloma genesis in patients with ...
L. Locke   +8 more
semanticscholar   +1 more source

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