Results 31 to 40 of about 63,225 (201)

Photodynamic Therapy for Granuloma Annulare: More than a Shot in the Dark [PDF]

, 2008
Granuloma annulare (GA) is a benign granulomatous and inflammatory skin disorder. The pathogenesis remains enigmatic and convincingly effective treatment options are not available.
Berking, Carola, Kuznetsov, Alexander Vasilevic, Molin, Sonja, Prinz, Jörg Christoph, Ruzicka, Thomas, Weisenseel, Peter   +5 more
core   +1 more source

T Cell Interactions in Mycobacterial Granulomas: Non-Specific T Cells Regulate Mycobacteria-Specific T Cells in Granulomatous Lesions

Cells, 2021
Infections with pathogenic mycobacteria are controlled by the formation of a unique structure known as a granuloma. The granuloma represents a host–pathogen interface where bacteria are killed and confined by the host response, but also where bacteria ...
Dominic O. Co, Laura H. Hogan, Jozsef Karman, Melinda Herbath, Zsuzsanna Fabry, Matyas Sandor   +5 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Eosinophilic ulcer of the tongue - Case report. [PDF]

, 2015
Eosinophilic ulcer of the oral mucosa is a rare, self-limiting, chronic and benign lesion of unknown pathogenesis that affects the oral mucosa. We present the case of a 65 year-old Caucasian female with a fivemonth history of a painful ulcer on the ...
Calvieri, Stefano, Didona, B, Didona, D, Donati, M, Paolino, Giovanni   +4 more
core   +2 more sources

Matrix Metalloproteinase-12 Is Required for Granuloma Progression

Frontiers in Immunology, 2020
BackgroundSarcoidosis is a chronic inflammatory disease of unknown cause characterized by granuloma formation. Mechanisms for chronic persistence of granulomas are unknown.
Arjun Mohan, Nicole Neequaye, Anagha Malur, Eman Soliman, Eman Soliman, Matthew McPeek, Nancy Leffler, David Ogburn, Debra A. Tokarz, Warren Knudson, Sina A. Gharib, Lynn M. Schnapp, Barbara P. Barna, Mary Jane Thomassen   +13 more
doaj   +1 more source

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. [PDF]

, 2018
Epithelial surfaces form critical barriers to the outside world and are continuously renewed by adult stem cells1. Whereas dynamics of epithelial stem cells during homeostasis are increasingly well understood, how stem cells are redirected from a tissue ...
de Sauvage, Frederic J, Klein, Ophir D, Landman, Tyler A, Locksley, Richard M, Marangoni, Pauline, Nusse, Ysbrand M, Rosendahl-Huber, Axel KM, Savage, Adam K   +7 more
core  

Texture features based microscopic image classification of liver cellular granuloma using artificial neural networks [PDF]

, 2019
Automated classification of Schistosoma mansoni granulomatous microscopic images of mice liver using Artificial Intelligence (AI) technologies is a key issue for accurate diagnosis and treatment.
Chen, Gaoxiang, Chen, Yating, Dey, Nilanjan, Sherratt, R. Simon, Shi, Fuqian, Wang, Yu, Yang, Ningning   +6 more
core   +1 more source

CSF cytokine, chemokine and injury biomarker profile of glial fibrillary acidic protein (GFAP) autoimmunity

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 855-860, April 2025.
Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal, Georgios Mangioris, Vanda Lennon, Binxia Yang, Divyanshu Dubey, Eoin P. Flanagan, Andrew McKeon, John R. Mills, Michel Toledano, Ivana Vodopivec, Sean J. Pittock, Anastasia Zekeridou   +11 more
wiley   +1 more source

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]

, 2013
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi, A Fortin, A Kahnert, A Mantovani, AM Becker, Anna Giagu, Antonio Giovanni Anfossi, CY Chen, DM Carragher, DM Lowe, E Corsiero, Elisabetta Antuofermo, F Mattei, Fabrizio Mattei, Filippo Belardelli, G Delogu, G Schiavoni, Giovanna Schiavoni, Giovanni Delogu, Giovanni Fadda, HP Gideon, Ivana Palucci, JF Marquis, JG Egen, JL Flynn, K Turcotte, K Turcotte, KB Urdahl, KK Huynh, L Gabriele, L Guglani, L Ramakrishnan, Laura Abalsamo, Lucia Gabriele, M Behr, M Munder, M Sali, Massimo Sanchez, MC Tsai, ME El Shikh, Michela Sali, MP Berry, NA Giese, Olivier Neyrolles, P Tailor, PJ Maglione, RL Hunter, S Hambleton, S Kunnath-Velayudhan, SA Luther, SS Kashino, Stefano Rocca, SY Foo, T Holtschke, T Ulrichs, TA Day, TD Randall, X Zhou, Y Yoshikai   +58 more
core   +6 more sources

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams, Afanasev, Alina E. Gorna, Aly, Arnold, Bacon, Banu, Bergval, Betts, Boshoff, Boshoff, Bostanabad, Burney, Capelli, Chan, Chan, Cheng, Cooper, Cubillos-Ruiz, Darwin, Darwin, Das, Davis, Dos Vultos, Dubnau, Durbach, Farnia, Fennelly, Filliol, Fleischmann, Flint, Fontan, Friedberg, Frischkorn, Fu, Fu, Gaynor, Gordhan, Graham, Grishko, Guthlein, Hampshire, Hazbon, Hughes, Jain, Jaroslaw Dziadek, Jiao, Kapur, Karakousis, Karakousis, Karunkaran, Katti, Kesavan, Kim, Ko, Ko, Korycka-Machala, Krokan, Kurthkoti, Kurthkoti, Lari, Lever, Loudon, MacMicking, Malshetty, Martinez, Mokrousov, Moller, Movahedzadeh, Mulder, Munoz-Elias, Muttucumaru, Nguyen, Niemann, Nikolayevskyy, Nouvel, O'sullivan, Olano, Peccia, Peccia, Pitcher, Rachman, Rachman, Rad, Ramaswamy, Richard P. Bowater, Riley, Saito, Sander, Sassetti, Sassetti, Saunders, Schnappinger, Schwab, Sherman, Sinha, Sinha, Smeulders, Springer, Srivastava, Stephanou, Talaat, Talaat, Tang, Tsai, Venkatesh, Vilcheze, Voskuil, Voskuil, Waddell, Wanner, Warner, Weikert, Wiid, Wiseman, World Health Organization, Zaczek, Zainuddin   +117 more
core   +1 more source