Results 1 to 10 of about 1,240,530 (301)
Aspergillosis in Chronic Granulomatous Disease [PDF]
Journal of Fungi, 2016 Patients with chronic granulomatous disease (CGD) have the highest life-time incidence of invasive aspergillosis and despite the availability of antifungal prophylaxis, infections by Aspergillus species remain the single most common infectious cause of ...
Jill King +2 more
doaj +6 more sources
Chronic granulomatous disease [PDF]
Indian Dermatology Online Journal, 2015 Chronic Granulomatous Disease (CGD) is an inherited immunodeficiency disorder characterized by defective functioning of NADPH oxidase enzyme in the phagocytes.
Kikkeri Narayanasetty Naveen +1 more
doaj +7 more sources
Chronic Granulomatous Disease [PDF]
British Medical Bulletin, 2016 INTRODUCTION Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent, life-threatening bacterial and fungal infections of the skin, the airways, the lymph nodes, the liver, the brain and the bones.
A. Rawat, S. Bhattad, Surjit Singh
semanticscholar +9 more sources
Cellular Therapies in Chronic Granulomatous Disease
Frontiers in Pediatrics, 2020 Allogeneic hematopoietic stem cell transplantation (HSCT) has become the main curative treatment in patients with chronic granulomatous disease (CGD). CGD is caused by inherited defects of the phagolysomal NADPH-oxidase, leading to a lifelong propensity ...
Tayfun Güngör, Robert Chiesa
doaj +2 more sources
A Review of Chronic Granulomatous Disease [PDF]
Advances in Therapy, 2017 Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defects in any of the five subunits of the NADPH oxidase complex responsible for the respiratory burst in phagocytic leukocytes.
Danielle E. Arnold, J. Heimall
semanticscholar +3 more sources
Chronic granulomatous disease: the European experience.
PLoS ONE, 2009 CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex. Normally, assembly of the NADPH oxidase complex in phagosomes of certain phagocytic cells leads to a "respiratory burst ...
J Merlijn van den Berg +18 more
doaj +9 more sources
Frontiers in Immunology, 2021 Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri +20 more
doaj +1 more source
A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
Dermatology Reports, 2022 We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco +2 more
doaj +1 more source
Hematology/Oncology Clinics of North America, 2009 Chronic granulomatous disease (CGD) was first described in the 1950s and has become a paradigm for genetic neutrophil diseases. It is characterized by recurrent infections with a narrow spectrum of bacteria and fungi as well as a common set of inflammatory complications most notably including inflammatory bowel disease. Over the last half century major
Stasia, Marie José +3 more
+12 more sources
Asian Pacific Journal of Tropical Medicine, 2022 Objective: To investigate granulomatous inflammation etiology based on clinical history and ancillary tests. Methods: Children aged
Ummühan Cay +4 more
doaj +1 more source