Results 1 to 10 of about 57,847 (151)
Chronic granulomatous disease [PDF]
Indian Dermatology Online Journal, 2015 Chronic Granulomatous Disease (CGD) is an inherited immunodeficiency disorder characterized by defective functioning of NADPH oxidase enzyme in the phagocytes.
Kikkeri Narayanasetty Naveen +1 more
doaj +6 more sources
Chronic granulomatous disease [PDF]
British Medical Bulletin, 2016 Chronic granulomatous disease is a clinical condition that stems from inactivating mutations in NOX2 and its auxiliary proteins. Together, these proteins form the phagocyte NADPH oxidase enzyme that generates superoxide. Superoxide (O2ċ-) and its reduced product hydrogen peroxide (H2O2) give rise to several additional reactive oxygen species (ROS ...
Amit, Rawat +2 more
+8 more sources
Frontiers in Immunology, 2021 Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri +20 more
doaj +1 more source
A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
Dermatology Reports, 2022 We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco +2 more
doaj +1 more source
Chronic granulomatous disease [PDF]
Pediatric Radiology, 2010 Chronic granulomatous disease (CGD) is a rare congenital immunodeficiency characterized by recurrent bacterial and fungal infections as well as granuloma formation. The manifestations of this disease can involve single or multiple organ systems. The lungs are the most commonly affected organ; however, lymphatic, hepatic, skeletal, gastrointestinal ...
Alexander J, Towbin, Ian, Chaves
+6 more sources
Chronic granulomatous disease [PDF]
Clinical and Experimental Immunology, 2000 A clinical syndrome characterized by recurrent life-threatening Staphylococcus aureus, Proteus or Pseudomonas, hypergammaglobulinaemia, and widespread chronic granulomatous infiltration was first recognized in the paediatric literature between 1954 and 1960 [1–3].
D, Goldblatt, A J, Thrasher
openaire +4 more sources
Asian Pacific Journal of Tropical Medicine, 2022 Objective: To investigate granulomatous inflammation etiology based on clinical history and ancillary tests. Methods: Children aged
Ummühan Cay +4 more
doaj +1 more source
Chronic granulomatous disease [PDF]
The British Journal of Radiology, 1970 Abstract Chronic granulomatous disease is a hereditable disorder in which polymorphs show diminished capacity for killing bacteria. Defective bactericidal activity results in protracted infection. The lesions of chronic granulomatous disease may affect all systems of the body.
J, Sutcliffe, A R, Chrispin
openaire +4 more sources
Clinical observation of Сhronic granulomatous disease in a 6-year-old child
Детские инфекции (Москва), 2020 Chronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis.
G. A. Kharchenko, O. G. Kimirilova
doaj +1 more source
Frontiers in Immunology, 2023 Chronic granulomatous disease is an inborn error of immunity due to disrupted function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex.
Julia Scheiermann +22 more
doaj +1 more source