Results 11 to 20 of about 5,872,109 (287)
Aspergillosis in Chronic Granulomatous Disease [PDF]
Patients with chronic granulomatous disease (CGD) have the highest life-time incidence of invasive aspergillosis and despite the availability of antifungal prophylaxis, infections by Aspergillus species remain the single most common infectious cause of ...
Adilia Warris
exaly +6 more sources
Chronic granulomatous disease [PDF]
Chronic Granulomatous Disease (CGD) is an inherited immunodeficiency disorder characterized by defective functioning of NADPH oxidase enzyme in the phagocytes.
Kikkeri Narayanasetty Naveen +1 more
doaj +6 more sources
Chronic granulomatous disease: the European experience. [PDF]
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex. Normally, assembly of the NADPH oxidase complex in phagosomes of certain phagocytic cells leads to a "respiratory burst ...
J Merlijn van den Berg +18 more
doaj +3 more sources
A Review of Chronic Granulomatous Disease [PDF]
Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defects in any of the five subunits of the NADPH oxidase complex responsible for the respiratory burst in phagocytic leukocytes. Patients with CGD are at increased risk of life-threatening infections with catalase-positive bacteria and fungi and inflammatory complications such ...
Danielle Arnold
exaly +3 more sources
Granulibacter bethesdensis is a pathogen reported to cause recurrent lymphadenitis exclusively in persons with chronic granulomatous disease. We report a case of fatal meningitis caused by a highly virulent G.
Mafalda Rebelo +7 more
doaj +2 more sources
Chronic granulomatous disease [PDF]
Chronic granulomatous disease is a clinical condition that stems from inactivating mutations in NOX2 and its auxiliary proteins. Together, these proteins form the phagocyte NADPH oxidase enzyme that generates superoxide. Superoxide (O2ċ-) and its reduced product hydrogen peroxide (H2O2) give rise to several additional reactive oxygen species (ROS ...
Amit, Rawat +2 more
openaire +6 more sources
Preventing Chronic Disease (PCD) [PDF]
This collection of articles in Preventing Chronic Disease (PCD) brings together scientists and practitioners from the breadth of public health and the social sciences to demonstrate how geospatial perspectives can contribute to understanding and ...
core +11 more sources
Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri +20 more
doaj +1 more source
A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco +2 more
doaj +1 more source
Chronic granulomatous disease [PDF]
Abstract Chronic granulomatous disease is a hereditable disorder in which polymorphs show diminished capacity for killing bacteria. Defective bactericidal activity results in protracted infection. The lesions of chronic granulomatous disease may affect all systems of the body.
J, Sutcliffe, A R, Chrispin
openaire +4 more sources

