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Sarcoidosis-associated hepatocellular carcinoma [PDF]
Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma
Aiko, Satoshi+7 more
core +1 more source
Chronic granulomatous disease is an inborn error of immunity due to disrupted function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex.
Julia Scheiermann+22 more
doaj +1 more source
Chronic granulomatous disease [PDF]
Chronic granulomatous disease (CGD) is a rare congenital immunodeficiency characterized by recurrent bacterial and fungal infections as well as granuloma formation. The manifestations of this disease can involve single or multiple organ systems. The lungs are the most commonly affected organ; however, lymphatic, hepatic, skeletal, gastrointestinal ...
Alexander J. Towbin, Ian J. Chaves
openaire +4 more sources
Chronic Granulomatous Disease: the Experience of Diagnosis and Treatment in Children
Chronic granulomatous disease — primary immunodeficiency with X-linked and autosomal recessive inheritance, characterized by impaired bactericidal function of phagocytic immune system.
L.I. Chernyshova+4 more
doaj +1 more source
Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner+7 more
core +3 more sources
Chronic granulomatous disease [PDF]
A clinical syndrome characterized by recurrent life-threatening Staphylococcus aureus, Proteus or Pseudomonas, hypergammaglobulinaemia, and widespread chronic granulomatous infiltration was first recognized in the paediatric literature between 1954 and 1960 [1–3].
Adrian J. Thrasher, David Goldblatt
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Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis [PDF]
Acknowledgements: The authors would like to acknowledge Fraser P. Coxon and Ian Ganley for providing LC3-GFP-mCherry BMDMs. M.S.G. was supported by an FEMS research grant and F.L.v.d.V.
Alonso, M Fernanda+8 more
core +2 more sources
In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD+3 more
core +1 more source
Lacrimal gland tumors in Turkey: types, frequency, and outcomes. [PDF]
AIM: To evaluate the clinical, radiological, and treatment features of lacrimal gland tumors. METHODS: Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March ...
Erden, Esra+3 more
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A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan+19 more
wiley +1 more source