Results 21 to 30 of about 89,859 (293)
Recent advances in chronic granulomatous disease
Genes and Diseases, 2020 Chronic granulomatous disease (CGD) is an inherited defect of phagocyte function due to defective NADPH oxidase. Patients with CGD are not able to effectively clear the infections because of the defect in the phagocyte production of oxygen free radicals ...
Gummadi Anjani +6 more
doaj +1 more source
BCGiosis as a presenting feature of a child with chronic granulomatous disease
Brazilian Journal of Infectious Diseases, 2011 Bacillus Calmette Guerin (BCG) vaccine, which is administered to all newborns in some regions, could lead to serious complication ranging from local disease (known as BCGitis) to disseminated disease (BCGosis) in a group of patients with primary ...
Zahra Movahedi +3 more
doaj +1 more source
Cellular Therapies in Chronic Granulomatous Disease
Frontiers in Pediatrics, 2020 Allogeneic hematopoietic stem cell transplantation (HSCT) has become the main curative treatment in patients with chronic granulomatous disease (CGD). CGD is caused by inherited defects of the phagolysomal NADPH-oxidase, leading to a lifelong propensity ...
Tayfun Güngör, Robert Chiesa
doaj +1 more source
Sarcoidosis-associated hepatocellular carcinoma [PDF]
, 2010 Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma
Aiko, Satoshi +7 more
core +1 more source
Emerging Infectious Diseases, 2019 Granulibacter bethesdensis is a pathogen reported to cause recurrent lymphadenitis exclusively in persons with chronic granulomatous disease. We report a case of fatal meningitis caused by a highly virulent G.
Mafalda Rebelo +7 more
doaj +1 more source
Frontiers in Medicine, 2021 Uveitis associated with Vogt-Koyanagi-Harada (VKH) disease is a bilateral, chronic, granulomatous autoimmune disease associated with vitiligo, poliosis, alopecia, and meningeal and auditory manifestations.
Ahmed M. Abu El-Asrar +4 more
doaj +1 more source
In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]
, 2008 Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD +3 more
core +1 more source
Chronic granulomatous disease: why an inflammatory disease?
Brazilian Journal of Medical and Biological Research, 2014 Chronic granulomatous disease is a primary immunodeficiency caused by mutations in the genes encoding subunits of the phagocytic NADPH oxidase system. Patients can present with severe, recurrent infections and noninfectious conditions.
P. Roxo-Junior, H.M.L. Simão
doaj +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Atypical Presentation of Chronic Granulomatous Disease in a Child
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2017 Chronic granulomatous disease is a rare, inherited immunodeficiency caused by deletions or mutations in genes that encode subunits of the NADPH oxidase complex. The pattern of chronic granulomatous disease inheritance can be X-linked (about 70% of cases)
Chiara Cuzzupè +7 more
doaj +1 more source