Results 71 to 80 of about 1,286,383 (333)

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

FAMILIAL CHRONIC GRANULOMATOUS DISEASE

Pakistan Armed Forces Medical Journal, 2019
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder of phagocytes, characterized by repeated bacterial and fungal infections.
Tariq Ghafoor, Farrah Bashir
doaj  

A Rare Form of Chronic Granulomatous Disease (Type Iva) Presenting as Inflammatory Bowel Disease

Canadian Journal of Gastroenterology, 1996
Neutrophil dysfunction syndromes can sometimes mimic the clinical and pathological features of inflammatory bowel disease. The case of a 3.5-year-old boy with chronic diarrhea, abdominal pain, poor growth since infancy and microcytic, hypochromic anemia ...
Francisco A Sylvester
doaj   +1 more source

Chronic Crohn’s disease: diagnosis and management at the present times

Zdorovʹe Rebenka, 2018
The article deals with the data on the prevalence, diagnosis, treatment, prevention of bacterial and fungal infections in children with chronic granulomatous disease.
V.A. Klimenko, O.V. Piontkovska, O.S. Lupaltseva, T.O. Khalturina, O.M. Savvo, N.I. Timokhina, G.M. Soboleva   +6 more
doaj   +1 more source

COVID-19 in Chronic Granulomatosis Disease: A Case Report

Iranian Journal of Allergy, Asthma and Immunology, 2022
A novel coronavirus disease known as Coronavirus Disease 2019 (COVID-19) has spread quickly throughout the world, and it was declared a pandemic in March 2022.
Hossein Esmaeilzadeh, Seyed Sina Dehghani, Babak Shahhoseini, Soheila Alyasin, Sayyed Hesamedin Nabavizadeh, Aida Askari   +5 more
doaj   +1 more source

Biocompatibility and healing patterns in experimentally induced canine tibial fractures using Pedicle screw‐Rod external fixation

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that using a Pedicle screw‐Rod configuration for the external fixation of non‐articular tibial osteotomy aligns well with the principles of biological osteosynthesis, resulting in secondary bone healing characterized by callus formation and neovascularization.
Mohammad Mahdi Gooran, Ramin Mazaheri‐Khameneh, Seyed Mohammad Hashemi‐Asl, Rahim Hobbenaghi   +3 more
wiley   +1 more source

The Multiple Faces of Nitric Oxide in Chronic Granulomatous Disease: A Comprehensive Update

Biomedicines, 2022
Nitric oxide (NO), a signaling molecule, regulates multiple biological functions, including a variety of physiological and pathological processes. In this regard, NO participates in cutaneous inflammations, modulation of mitochondrial functions, vascular
Juan Agustín Garay, Juan Eduardo Silva, María Silvia Di Genaro, Roberto Carlos Davicino   +3 more
doaj   +1 more source

Targeted Gene Addition to a Safe Harbor locus in human CD34+ Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease

Nature Biotechnology, 2016
Gene therapy with genetically modified human CD34+ hematopoietic stem and progenitor cells (HSPCs) may be safer using targeted integration (TI) of transgenes into a genomic 'safe harbor' site rather than random viral integration.
S. de Ravin, A. Reik, Pei‐Qi Liu, Linhong Li, Xiaolin Wu, Ling Su, C. Raley, N. Theobald, U. Choi, Alexander H Song, Andy Chan, Jocelynn R Pearl, David E. Paschon, Janet Lee, H. Newcombe, S. Koontz, C. Sweeney, David A. Shivak, K. Zarember, M. Peshwa, P. Gregory, F. Urnov, H. Malech   +22 more
semanticscholar   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

A Case of Chronic Granulomatous Disease with a Necrotic Mass in the Bronchus: A Case Report and a Review of Literature

Case Reports in Pulmonology, 2012
Chronic granulomatous disease is a rare phagocytic disorder with recurrent, severe bacterial and fungal infections. We describe an unusual case of chronic granulomatous disease manifesting as an invasive pulmonary aspergillosis with an obstructive ...
Ali Cheraghvandi, Majid Marjani, Saeid Fallah Tafti, Logman Cheraghvandi, Davoud Mansouri   +4 more
doaj   +1 more source