Results 71 to 80 of about 1,267,460 (316)

Targeted Gene Addition to a Safe Harbor locus in human CD34+ Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease

open access: yesNature Biotechnology, 2016
Gene therapy with genetically modified human CD34+ hematopoietic stem and progenitor cells (HSPCs) may be safer using targeted integration (TI) of transgenes into a genomic 'safe harbor' site rather than random viral integration.
S. de Ravin   +22 more
semanticscholar   +1 more source

Coccidiomycosis infection of the patella mimicking a neoplasm - two case reports. [PDF]

open access: yes, 2014
BackgroundCoccidioidomycosis is an endemic fungal infection in the southwestern of United States. Most infections are asymptomatic or manifest with mild respiratory complaints. Rare cases may cause extrapulmonary or disseminated disease.
Calvert, George   +4 more
core   +1 more source

The Multiple Faces of Nitric Oxide in Chronic Granulomatous Disease: A Comprehensive Update

open access: yesBiomedicines, 2022
Nitric oxide (NO), a signaling molecule, regulates multiple biological functions, including a variety of physiological and pathological processes. In this regard, NO participates in cutaneous inflammations, modulation of mitochondrial functions, vascular
Juan Agustín Garay   +3 more
doaj   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience.

open access: yesBlood, 2016
Chronic granulomatous disease (CGD) can be cured by allogeneic hemopoietic stem cell transplantation (HSCT). Complications include graft failure, graft-versus-host disease (GVHD), infection, and transplant-related mortality; therefore, reduced-intensity ...
B. Morillo-Gutiérrez   +22 more
semanticscholar   +1 more source

Causes of mortality and characterisation of Mycobacteriosis in adult New Zealand sea lions (Phocarctos Hookeri) at Enderby Island : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science in Wildlife Health at Massey University, Manawatū, Palmerston North, New Zealand [PDF]

open access: yes, 2017
The New Zealand sea lion (Phocarctos hookeri) is classified as endangered and “Nationally Critical” due to a declining population and restricted population range. There have been recent bacterial epizootic events at the breeding colonies of this species,
Lenting, Baukje Mirjam
core  

Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis [PDF]

open access: yes, 2005
Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis.
Gallimore, A, Lund, VJ, Paun, S
core   +1 more source

FAMILIAL CHRONIC GRANULOMATOUS DISEASE

open access: yesPakistan Armed Forces Medical Journal, 2019
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder of phagocytes, characterized by repeated bacterial and fungal infections.
Tariq Ghafoor, Farrah Bashir
doaj  

A Rare Form of Chronic Granulomatous Disease (Type Iva) Presenting as Inflammatory Bowel Disease

open access: yesCanadian Journal of Gastroenterology, 1996
Neutrophil dysfunction syndromes can sometimes mimic the clinical and pathological features of inflammatory bowel disease. The case of a 3.5-year-old boy with chronic diarrhea, abdominal pain, poor growth since infancy and microcytic, hypochromic anemia ...
Francisco A Sylvester
doaj   +1 more source

Cytomorphology in Tuberculous Lymphadenitis and Correlation With Acid Fast Bacilli Detection by Papanicolaou, Auramine‐Rhodamine Fluorescence and Ziehl‐Neelsen Techniques

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background Tuberculosis (TB) is a common cause of lymphadenopathy in developing countries. Fine needle aspiration cytology (FNAC) along with acid fast bacilli (AFB) detection is an invaluable diagnostic test. Fluorescent methods for AFB detection have greater sensitivity as compared to the Ziehl‐Neelsen (ZN) method. Methods The incidence of TB
Seethalakshmi Viswanathan, C. P. Shroff
wiley   +1 more source

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