Results 71 to 80 of about 1,240,530 (301)
The Multiple Faces of Nitric Oxide in Chronic Granulomatous Disease: A Comprehensive Update
Biomedicines, 2022 Nitric oxide (NO), a signaling molecule, regulates multiple biological functions, including a variety of physiological and pathological processes. In this regard, NO participates in cutaneous inflammations, modulation of mitochondrial functions, vascular
Juan Agustín Garay +3 more
doaj +1 more source
Nature Biotechnology, 2016 Gene therapy with genetically modified human CD34+ hematopoietic stem and progenitor cells (HSPCs) may be safer using targeted integration (TI) of transgenes into a genomic 'safe harbor' site rather than random viral integration.
S. de Ravin +22 more
semanticscholar +1 more source
Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies
Advanced Science, EarlyView.This review article delves into the cutting‐edge advancements in gene editing technology, with a particular focus on prime editor proteins and their engineered variants. The authors provide a thorough examination of recent developments that have addressed key challenges in the field, including improved precision, enhanced editing efficiency, and ...
Abhijith Koodamvetty +1 more
wiley +1 more source
Advanced Science, EarlyView.With the intensification of aging issues, inflammatory orthopedic diseases almost occurs in every elderly people, which are becoming increasingly severe. Persistent inflammation of joints often leads to irreversible tissue damage and loss of organ function, while early diagnosis and timely intervention are crucial for reducing the personal and social ...
Mengyi Huang +7 more
wiley +1 more source
FAMILIAL CHRONIC GRANULOMATOUS DISEASE
Pakistan Armed Forces Medical Journal, 2019 Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder of phagocytes, characterized by repeated bacterial and fungal infections.
Tariq Ghafoor, Farrah Bashir
doaj
Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases
Advanced Science, EarlyView.This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou +4 more
wiley +1 more source
Dataset Optimization for Chronic Disease Prediction with Bio-Inspired Feature Selection [PDF]
arXiv, 2023 In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The primary goal was to enhance the predictive accuracy of models streamline data dimensionality, and make predictions ...
arxiv
Staphylococcus aureus, phagocyte NADPH oxidase and chronic granulomatous disease
FEMS Microbiology Reviews, 2016 Dysfunction of phagocytes is a relevant risk factor for staphylococcal infection. The most common hereditary phagocyte dysfunction is chronic granulomatous disease (CGD), characterized by impaired generation of reactive oxygen species (ROS) due to loss ...
H. Buvelot +4 more
semanticscholar +1 more source
Chronic Granulomatous Disease in Patients Reaching Adulthood: A Nationwide Study in France
Clinical Infectious Diseases, 2017 Background Although prognosis of Chronic Granulomatous Disease (CGD) has greatly improved, few studies have focused on its long-term outcome. We studied the clinical course and sequelae of CGD patients diagnosed before age 16, at various adult time ...
B. Dunogué +24 more
semanticscholar +1 more source
A comprehensive review of Chronic Kidney Disease of Unknown Etiology [PDF]
arXiv, 2018 This review was written to provide a comprehensive summary of the suggested etiologies of Chronic Kidney Disease of Unknown Etiology (CKDu) in Sri Lanka. In this review, Chronic Kidney Disease (CKD) is explained in detail and its known etiologies are discussed.
arxiv