An Unusual Orthopaedic Disease: Sarcoidosis—A Case Report
The Surgery Journal, 2017 Sarcoidosis is an idiopathic, noncaseating granulomatous disorder with wide systemic involvement. It is encountered widely around the world and it affects both sexes, all the races in all age groups.
Bahattin Kemah +5 more
doaj +1 more source
Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling [PDF]
, 2018 Cellular activation in trans by interferons, cytokines and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with
Andrews, Paul S. +8 more
core +4 more sources
Journal of Periodontology, EarlyView.Abstract Background The exponential increase in dental implant use has led to a parallel rise in peri‐implant diseases (PID), adversely affecting implant therapy success and patient quality of life. Efforts have been made by the dental community to understand systemic, behavioral, and site‐level risk factors involved in the etiologies and pathogenesis ...
Hom‐Lay Wang +59 more
wiley +1 more source
Definitions, 2013 Chronic granulomatous disease is a disorder that causes the immune system to malfunction, resulting in a form of immunodeficiency. Immunodeficiencies are conditions in which the immune system is not able to protect the body from foreign invaders such as ...
V. M. Suárez +7 more
semanticscholar +1 more source
Upadacitinib for difficult‐to‐treat paediatric Crohn's disease
JPGN Reports, EarlyView.Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou +3 more
wiley +1 more source
NOD2 and inflammation: current insights [PDF]
, 2018 The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and promotes their clearance through activation of a proinflammatory ...
Cucchiara, Salvatore +3 more
core +2 more sources
Genital Crohn's disease in pediatrics and genetic associations
JPGN Reports, EarlyView.Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang +5 more
wiley +1 more source
Causes of mortality and characterisation of Mycobacteriosis in adult New Zealand sea lions (Phocarctos Hookeri) at Enderby Island : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science in Wildlife Health at Massey University, Manawatū, Palmerston North, New Zealand [PDF]
, 2017 The New Zealand sea lion (Phocarctos hookeri) is classified as endangered and “Nationally Critical” due to a declining population and restricted population range. There have been recent bacterial epizootic events at the breeding colonies of this species,
Lenting, Baukje Mirjam
core
Lentiviral gene therapy for X-linked chronic granulomatous disease
Nature Network Boston, 2020 D. Kohn +41 more
semanticscholar +1 more source
Eosinophilic mesenteric vasculitis presenting as inflammatory bowel disease
JPGN Reports, EarlyView.Abstract Inflammatory bowel disease (IBD), including Crohn's Disease (CD) and ulcerative colitis, is a chronic inflammatory condition affecting the gastrointestinal tract. Treatment for IBD depends on disease severity and can include medical and surgical management.
Razan Alkhouri +7 more
wiley +1 more source