Results 181 to 190 of about 88,726 (230)
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The Lancet, 1969
Abstract Significant abnormality of nitroblue tetrazolium (N.B.T.) oxidation, and of bacterial killing, in the fathers of patients with chronic granulomatous disease suggests a pattern of sex-modified autosomal recessive inheritance. The data suggest that the defect may be much commoner than is at present recognised.
JackC. Bass, StellaB. Kontras
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Abstract Significant abnormality of nitroblue tetrazolium (N.B.T.) oxidation, and of bacterial killing, in the fathers of patients with chronic granulomatous disease suggests a pattern of sex-modified autosomal recessive inheritance. The data suggest that the defect may be much commoner than is at present recognised.
JackC. Bass, StellaB. Kontras
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Granulomatous annular diseases
Clinics in Dermatology, 2023Granulomatous skin disorders comprise a large group of diseases that are typically characterized by granuloma formation both in the skin and in many other tissues. Cutaneous lesions are usually seen as erythematous papules and plaques that may occasionally be arranged in an annular, ringlike configuration. The etiopathogenesis is unclear in most cases,
Uzuncakmak, Tugba Kevser +2 more
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Pediatric and Developmental Pathology, 2003
CLINICAL SUMMARY A 3-year-old African-American boy presented with limping due to a thigh mass of recent appearance. The lesion was initially painless and nonmobile, without erythema or swelling. There was no fever or other constitutional symptom. Four days before admission, a second tumor appeared on the left parietal region.
Rebecca E. Rosenberg +4 more
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CLINICAL SUMMARY A 3-year-old African-American boy presented with limping due to a thigh mass of recent appearance. The lesion was initially painless and nonmobile, without erythema or swelling. There was no fever or other constitutional symptom. Four days before admission, a second tumor appeared on the left parietal region.
Rebecca E. Rosenberg +4 more
openaire +6 more sources
Pediatric Radiology, 1981
The report describes a ten year old boy with a form of chronic granulomatous disease characterised by hepatic and tibial granulomatous, hilar and broncopulmonar inflammatory processes, and an absolute defect in PMN-mediated ADCC.
F. Bassani +3 more
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The report describes a ten year old boy with a form of chronic granulomatous disease characterised by hepatic and tibial granulomatous, hilar and broncopulmonar inflammatory processes, and an absolute defect in PMN-mediated ADCC.
F. Bassani +3 more
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Acta Paediatrica, 1968
SummaryTwo brothers with Fatal granulomatous disease of childhood (FGD) are presented. Both patients exhibited pronounced food allergy. Otherwise, the course of the disease was typical of FGD. From infancy recurrent infections, notably suppurative lymphadenitis, and a fatal outcome before puberty.Microscopic examination of affected organs revealed ...
René Vejlsgaard +3 more
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SummaryTwo brothers with Fatal granulomatous disease of childhood (FGD) are presented. Both patients exhibited pronounced food allergy. Otherwise, the course of the disease was typical of FGD. From infancy recurrent infections, notably suppurative lymphadenitis, and a fatal outcome before puberty.Microscopic examination of affected organs revealed ...
René Vejlsgaard +3 more
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Dermatologic Clinics, 2020
Granulomatous diseases are chronic inflammatory disorders whose pathogenesis is triggered by an array of infectious and noninfectious agents, and may be localized or a manifestation of systemic, disseminated disease. As in the skin, oral manifestations of granulomatous inflammation are often nonspecific in their clinical appearance.
Faizan Alawi +3 more
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Granulomatous diseases are chronic inflammatory disorders whose pathogenesis is triggered by an array of infectious and noninfectious agents, and may be localized or a manifestation of systemic, disseminated disease. As in the skin, oral manifestations of granulomatous inflammation are often nonspecific in their clinical appearance.
Faizan Alawi +3 more
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Pediatric Radiology, 2010
Chronic granulomatous disease (CGD) is a rare congenital immunodeficiency characterized by recurrent bacterial and fungal infections as well as granuloma formation. The manifestations of this disease can involve single or multiple organ systems. The lungs are the most commonly affected organ; however, lymphatic, hepatic, skeletal, gastrointestinal ...
Alexander J. Towbin, Ian J. Chaves
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Chronic granulomatous disease (CGD) is a rare congenital immunodeficiency characterized by recurrent bacterial and fungal infections as well as granuloma formation. The manifestations of this disease can involve single or multiple organ systems. The lungs are the most commonly affected organ; however, lymphatic, hepatic, skeletal, gastrointestinal ...
Alexander J. Towbin, Ian J. Chaves
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Internal and Emergency Medicine, 2011
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency due to an abnormal function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase; NADPH oxidase is a key enzyme for the cellular "respiratory burst", the cellular process that converts molecular oxygen to the oxygen free-radical superoxide.
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Chronic granulomatous disease (CGD) is a rare primary immunodeficiency due to an abnormal function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase; NADPH oxidase is a key enzyme for the cellular "respiratory burst", the cellular process that converts molecular oxygen to the oxygen free-radical superoxide.
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Pediatric Clinics of North America, 1977
Since 1971, significant deviations from the classic pattern of chronic granulomatous disease have been recognized, and the disease appears to be more common that it did formerly. Knowledge of the basic underlying molecular defect has been broadened, and some new concepts of diagnosis and management have been formed. This report summarizes new knowledge
Richard B. Johnston, Simon L. Newman
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Since 1971, significant deviations from the classic pattern of chronic granulomatous disease have been recognized, and the disease appears to be more common that it did formerly. Knowledge of the basic underlying molecular defect has been broadened, and some new concepts of diagnosis and management have been formed. This report summarizes new knowledge
Richard B. Johnston, Simon L. Newman
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Current Treatment Options in Gastroenterology, 2000
In the United States, the majority of patients with granulomatous liver disease do not have an identifiable cause. When a specific diagnosis can be made, therapy should be directed at eradicating the cause. A plan of management must recognize the drug history and nationality of the patient, chest radiograph, slit lamp examination of the eyes, skin ...
Hamid Hussain, Martin Black
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In the United States, the majority of patients with granulomatous liver disease do not have an identifiable cause. When a specific diagnosis can be made, therapy should be directed at eradicating the cause. A plan of management must recognize the drug history and nationality of the patient, chest radiograph, slit lamp examination of the eyes, skin ...
Hamid Hussain, Martin Black
openaire +3 more sources