Results 81 to 90 of about 113,574 (281)

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately‐to‐Severely Active Crohn's Disease

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study aimed to characterize the pharmacokinetics (PK) of etrolizumab, an IgG1‐humanized monoclonal anti‐β7 integrin antibody, and assess its exposure–response (ER) relationship for key clinical outcomes in patients with moderately‐to‐severely active Crohn's disease.
Anita Moein   +4 more
wiley   +1 more source

What Immunological Defects Predispose to Non-tuberculosis Mycobacterial Infections? [PDF]

open access: yes, 2017
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil.  NTM cause a variety of diseases in humans that mainly affect the lung.
Adcock, IM   +7 more
core  

A rapid and automated primary screening platform for breast cancer percutaneous biopsies

open access: yesJournal of Intelligent Medicine, EarlyView.
Utilizing a 20 × 20 array plate, 3DHE technology demonstrates robust capability in distinguishing paracancer tissues from cancer tissues, effectively minimizing interference from nonspecific tumor proteins. This technique offers high sensitivity and is suitable for analyzing breast cancer needle biopsy samples.
Jiawei Gao   +5 more
wiley   +1 more source

Magnetic Resonance Imaging in the Clinical Evaluation of Lung Disorders: Current Status and Future Prospects

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The low proton density and high signal decay rate of pulmonary tissue have previously hampered the application of magnetic resonance imaging (MRI) in the clinical evaluation of lung disorders. With the continuing technical advances in scanners, coils, pulse sequences, and image postprocessing, pulmonary MRI can provide structural and ...
Linyu Wu   +7 more
wiley   +1 more source

Hodgkin's disease and granulomatous angiitis of the central nervous system [PDF]

open access: bronze, 1976
F. Anthony Greco   +3 more
openalex   +1 more source

A Novel In Vitro Host−Pathogen Model for Felis catus and Sporothrix Zoonotic Species Investigation

open access: yesJournal of Basic Microbiology, EarlyView.
ABSTRACT Hyperendemic zoonotic sporotrichosis, attributed to Sporothrix brasiliensis, presents a significant public health challenge in Brazil. Cats exhibit severe symptoms and high fungal loads, though their susceptibility is unclear. Sporothrix schenckii can also cause feline disease, primarily seen in Asia.
Gabriele Barros Mothé   +10 more
wiley   +1 more source

Specific phenotypes may drive an increased incidence of pediatric inflammatory bowel disease in South‐Eastern Norway

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric inflammatory bowel disease (PIBD) incidence has increased in recent decades but may be stabilizing, prompting exploration of incidence changes, disease distribution, and severity. Methods From 2017 to 2019, patients under 18 years with PIBD symptoms were recruited from nine hospitals in South‐Eastern Norway for ...
Svend Andersen   +12 more
wiley   +1 more source

Cow's milk protein allergy with protein‐losing enteropathy under the scope

open access: yesJPGN Reports, EarlyView.
ABSTRACT Objectives Cow's milk protein allergy (CMPA) is very frequent in infants. Presentation is variable, and symptoms fluctuate in intensity. Diagnosis can be challenging as it is mostly clinical. In severe cases, patients can present with anasarca secondary to protein‐losing enteropathy (PLE).
Morgane Thorens‐Borgeat   +6 more
wiley   +1 more source

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