Results 201 to 210 of about 79,933 (320)

Filamin A in the ovary: a mediator of granulosa cell functions. [PDF]

open access: yesReprod Fertil
Jiang Y   +9 more
europepmc   +1 more source

Nicotinamide Riboside Improves Mitochondrial Function and Oocyte Maturation in Aged Mice: A Multitarget Mechanistic Study Using Network Pharmacology and Molecular Simulations

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Mitochondrial dysfunction plays a critical role in ovarian aging and the associated decline in female fertility. Nicotinamide riboside (NR), a vitamin B3 derivative and dietary NAD+ precursor, has shown antiaging potential, yet its molecular mechanisms in ovarian function are not fully understood.
Ningyu Sun   +10 more
wiley   +1 more source

IMG-A1: A Novel Immortalized Granulosa Cell Line for Investigating FSH-Dependent Folliculogenesis and Ovarian Pathophysiology. [PDF]

open access: yesCells
Alyoshina NM   +10 more
europepmc   +1 more source

Excessive Vitamin E Supplementation: Implications for Ovarian Physiology and Reproductive Health

open access: yesOxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Infertility, a major global health problem affecting ~17.5% of couples, is influenced by various intrinsic (e.g., individual genetics) and extrinsic (e.g., related to environmental stimuli) factors. Oxidative stress and reactive oxygen species (ROS) are at the crossroads of these different stimulus–response pathways for both male and female gametes ...
Farzaneh Rabiee   +8 more
wiley   +1 more source

Granulosa Cell-Secreted KITL Is Involved in Maintaining Zinc Homeostasis in the Oocytes of Neonatal Mouse Ovaries. [PDF]

open access: yesAntioxidants (Basel)
Du Y   +10 more
europepmc   +1 more source

Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture [PDF]

open access: gold, 2017
Joseph A. Cacioppo   +5 more
openalex   +1 more source

Extracellular acidity and ATP modulate ion currents in human cumulus cells indicating possible roles as metabolic sensors of the follicular microenvironment

open access: yesPhysiological Reports, Volume 14, Issue 2, January 2026.
Extracellular acidity and ATP modify electrophysiological profile in human cumulus cell subpopulations, characterized by differential functional expression of TRPM5‐like, BKCa and KV1.5 currents. Abstract Cumulus cells (CCs), derived from granulosa cells, play a key role in supporting oocyte maturation and development through bidirectional ...
Andrea Biagini   +6 more
wiley   +1 more source

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