Results 41 to 50 of about 26,655 (253)

Diagnostic relevance of urinary steroid profiles on ovarian granulosa cell tumors: two case reports

Journal of Medical Case Reports, 2017
Background Granulosa cell tumor of the ovary is the most frequent sex cord stromal tumor and represents 2 to 5% of all primary ovarian cancers. Ovarian granulosa cell tumor is a malignant tumor with slow progression and in some cases this tumor is ...
Anita Bufa, Nelli Farkas, Zsolt Preisz, Viktória Poór, Csilla Páger, Sándor Szukits, Bálint Farkas, Péter Miklós Gőcze   +7 more
doaj   +1 more source

Expression of the DNA mismatch repair proteins hMLH1 and hPMS2 in normal human tissues. [PDF]

, 1997
hMLH1 and hPMS2 are part of the DNA mismatch repair complex. Mutations in these genes have been linked to hereditary non-polyposis colon cancer; they also occur in a variety of sporadic cancers. Western blot analysis and immunohistochemistry demonstrated
Aebi, S, Christen, RD, Fink, D, Howell, SB, Kim, HK, Nebel, S, Zheng, H   +6 more
core   +1 more source

Wnt5a Signaling in Normal and Cancer Stem Cells. [PDF]

, 2017
Wnt5a is involved in activating several noncanonical Wnt signaling pathways, which can inhibit or activate canonical Wnt/β-catenin signaling pathway in a receptor context-dependent manner.
Kipps, Thomas J, Zhang, Suping, Zhou, Yan   +2 more
core   +2 more sources

Juvenile granulosa cell tumor diagnosed in 6-month-old infant with precocious puberty

Radiology Case Reports, 2021
Juvenile granulosa cell tumor is a rare tumor diagnosed in children, which can present with precocious puberty. We have reported a case of a 6-month-old female patient who presented with precocious puberty.
Rebecca Hansen, MD, Austin Lewis, Christopher Sullivan, MDMPH, Leslie Hirsig, MDFAAP   +3 more
doaj  

Granulosa cell tumor of ovary: A clinicopathological study of four cases with brief review of literature

Journal of Mid-Life Health, 2014
Introduction: Adult granulosa cell tumor (GCT) is a rare ovarian malignancy having good prognosis in comparison with other epithelial tumors. The study aims to collect data of all granulosa cell tumors diagnosed in ESIC Medical College & PGIMSR ...
B R Vani, K Geethamala, R L Geetha, Murthy V Srinivasa   +3 more
doaj   +1 more source

Fertility preservation in ovarian tumours [PDF]

, 2018
A considerable number of patients with a cancer diagnosis are of childbearing age and have not satisfied their desire for a family. Despite ovarian cancer (OC) usually occurring in older patients, 3%–14% are diagnosed at a fertile age with the overall 5 ...
Bardhi, E., Di Donato, V., Di Pinto, A., Muzii, L., Panici, P. B., Peccatori, F. A., Petrella, M. C., Sassu, C. M., Tomao, F.   +8 more
core   +1 more source

Juvenile Granulosa Cell Tumors of the Testis: A Clinicopathologic Study of 70 Cases with Emphasis on Its Wide Morphologic Spectrum [PDF]

, 2015
The clinical and pathologic features of 70 juvenile granulosa cell tumors (JGCTs) of the testis are presented. The patients were from 30 weeks gestational age to 10 years old; 60 of 67 (90%) whose ages are known to us were 6 months old or younger.
Cornejo, Kristine M., Kao, Chia-Sui, Ulbright, Thomas M., Young, Robert H.   +3 more
core   +1 more source

N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]

, 2004
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V., Friese, K., Gundel, G., Jeschke, U., Mylonas, I., Müller, H., Richter, D.-U., Streu, A., Unverzagt, C.   +8 more
core   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

Advanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang, Jimmy Dhillon, Paul D. Soloway, Bo Shui, Seoyeon Lee, Jennifer K. Grenier, Paul R. Munn, M. Cecilia Ljungberg, Rebecca B Williams, Rainer B. Lanz, Yu‐Hsiang Liao, Yi A. Ren   +11 more
wiley   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

Animal Research and One Health, EarlyView.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang, Ao Guo, Lin Zhang, Shengru Wu, Juan Du, Taiyong Yu   +5 more
wiley   +1 more source