Results 41 to 50 of about 1,700,060 (216)
Diagnostic relevance of urinary steroid profiles on ovarian granulosa cell tumors: two case reports
Journal of Medical Case Reports, 2017 Background Granulosa cell tumor of the ovary is the most frequent sex cord stromal tumor and represents 2 to 5% of all primary ovarian cancers. Ovarian granulosa cell tumor is a malignant tumor with slow progression and in some cases this tumor is ...
Anita Bufa +7 more
doaj +1 more source
Immunohistochemical markers of prognosis in adult granulosa cell tumors of the ovary – a review
Journal of Ovarian Research, 2023 Background Granulosa cell tumors (GCT) are rare malignant ovarian tumors. The two subtypes, adult and juvenile granulosa cell tumors, differ in clinical and molecular characteristics.
Dennis Jung +6 more
semanticscholar +1 more source
Granulosa cell tumor of the ovary: a clinicopathological study of six cases
Journal of Pathology of Nepal, 2011 Background: Ovarian granulosa cell tumors are rare malignant neoplasms that originate from the sexcord stromal cells of the ovary. The study aims to collate data of all granulosa cell tumors diagnosed in Tribhuvan University Teaching Hospital over the ...
RC Adhikari, A Jha, G Shayami
doaj +1 more source
At Home Detection of Ovarian Health Biomarker in Menstruation Blood
Advanced Materials Technologies, EarlyView.A lateral flow assay enables the detection of anti‐Müllerian hormone directly in unprocessed menstrual blood using silica‐gold nanoshells and smartphone‐assisted machine learning analysis. The platform supports decentralized, user‐operated testing in wearable and dipstick formats, highlighting the potential of menstrual blood as a non‐invasive matrix ...
Lucas Dosnon +3 more
wiley +1 more source
Adult-type granulosa cell tumor of the testis: report of a case and review of literature
The Pan African Medical Journal, 2017 Granulosa cell tumors is classified into juvenile and adult types and comprise less than 5% of ovarian tumors in women and are much rarer in men which only 45 have been previously reported.
M. Elbachiri +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
Rare virilizing granulosa cell tumor in an adolescent.
Molecular and clinical oncology, 2017 Hormone-producing malignancies are rare in children or adolescent patients: Only 0.1% of all ovarian tumors and 4-5% of granulosa cell tumors occur in the sexually non-active ages.
D. Bús +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source
Oocyte–cumulus cell interaction: a key factor in early embryo development
Biological Reviews, EarlyView.ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source