Results 71 to 80 of about 5,590,804 (216)

Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer

World Journal of Surgical Oncology, 2010
Background Adult granulosa cell tumor associated with antecedent use of tamoxifen as adjuvant hormonotherapy for breast cancer is rare. The pathogenesis of this occurrence remains difficult to explain.
Abahssain Halima, Kairouani Mouna, Gherman Robert, M'Rabti Hind, Errihani Hassan   +4 more
doaj   +1 more source

Fertility-Preserving Surgery in a Young Nulligravid Woman with Bilateral Coexistence of a Granulosa Cell Tumor with a Teratoma

Case Reports in Obstetrics and Gynecology, 2023
Background. The coexistence of a granulosa cell tumor with a teratoma is extremely rare and impossible to diagnose preoperatively. For most patients with advanced age and stage, the standard treatment is hysterectomy and bilateral salpingo-oophorectomy ...
Pham Ba Nha, Pham Van Tuyen, Nguyen Viet Ha, Nguyen Thi Thu Phuong   +3 more
doaj   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Benign ovarian thecoma with markedly elevated serum inhibin B levels mimicking adult granulosa cell tumor

Gynecologic Oncology Reports, 2020
Introduction: Elevated serum inhibin B is a classic marker of adult granulosa cell tumors. Here we discuss an extremely rare and informative case of elevated inhibin B associated with an ovarian thecoma.
Erica V. Carballo, Kaley M. Gyorfi, Aleksandar K. Stanic, Paul Weisman, Christopher G. Flynn, David M. Kushner   +5 more
doaj   +1 more source

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

Cell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen, Xin Qi, Shanshan Qin, Jia Kang, Changhuo Cen, Miao Guo, Yang Gao, Mengyue Wang, Jiayi Li, Xiuhong Cui, Yanbo Wang, Lan Zhu, Fei Gao   +12 more
wiley   +1 more source

Exploring functional mechanisms underlying tumor initiation, EMT and cell migration [PDF]

, 2012
Cancer is one of the leading causes of death. A primary tumor forms when cells start to proliferate in an uncontrolled way and stop reacting to restraining signals.
Gruber, Dorothea Cornelia
core   +1 more source

Testicular torsion in foals and stallions

Equine Veterinary Education, EarlyView.
Summary Testicular torsion is a rare condition in horses characterised by a change in the position of the testis due to the testicular mesentery twisting around its own axis; it can occur both when the testis is still in the abdominal cavity and when it has descended into the scrotum.
C. P. Bartmann
wiley   +1 more source

Clinical and surgical findings in a mare with unilateral ovarian fibroleiomyoma and adhesions

Equine Veterinary Education, EarlyView.
Summary This case report describes the clinical presentation, ultrasonographic findings, surgical management and outcome of a 7‐year‐old Warmblood mare presented for recurrent colic, weight loss and poor performance. Rectal palpation identified a firm mass in the left caudal abdomen, which appeared on ultrasonography as a large, fluid‐filled, cyst‐like
N. Scilimati, P. Berni, E. Blanc, M. Di Pentima, F. Leonardi, S. Napoli, C. Palmieri, M. Ruggeri, R. Gialletti   +8 more
wiley   +1 more source

Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro [PDF]

, 2003
Oocyte control of granulosa and theca cell function may be mediated by several growth factors via a local feedback loop(s) between these cell types. This study examined both the role of oocyte-secreted factors on granulosa and thecal cells, cultured ...
Hunter, M.G., Brankin, V., Mitchell, M.R., Webb, B.   +3 more
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