Results 111 to 120 of about 10,360,699 (193)

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Leptin suppresses anti-Mullerian hormone gene expression through the JAK2/STAT3 pathway in luteinized granulosa cells of women undergoing IVF.

Human Reproduction, 2013
STUDY QUESTION Do the adipocytokines, leptin and adiponectin affect the granulosa cell expression of anti-Mullerian hormone (AMH) and its receptor (AMHR-II)?
Zaher Merhi, E. Buyuk, D. Berger, A. Zapantis, D. Israel, S. Chua, S. Jindal   +6 more
semanticscholar   +1 more source

Reproductive Biology of the Smoothtail Spiny Lobster (Panulirus laevicauda) to Support Fisheries Management in Southeastern Brazil

Fisheries Management and Ecology, EarlyView.
ABSTRACT The smoothtail spiny lobster (Panulirus laevicauda) is one of the main target species for fisheries in Brazil. We aimed to estimate reproductive parameters of this species in support of a minimum legal size limit for the region. A sample of 508 individuals ranged 13.75–100 mm in cephalothorax length (CL) from the southern coast of Espírito ...
Andressa C. M. de Melo, Luciano Pinto de Almeida, Glaucia Angelica Praxedes de Souza, Joelson Musiello‐Fernandes, Mauricio Hostim‐Silva, Jones Santander‐Neto   +5 more
wiley   +1 more source

FOXO1/3 depletion in granulosa cells alters follicle growth, death and regulation of pituitary FSH.

Molecular Endocrinology, 2013
The Forkhead boxO (FOXO) transcription factors regulate multiple cellular functions. FOXO1 and FOXO3 are highly expressed in granulosa cells of ovarian follicles. Selective depletion of the Foxo1 and Foxo3 genes in granulosa cells of mice reveals a novel
Zhilin Liu, D. Castrillon, W. Zhou, J. Richards   +3 more
semanticscholar   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source

Evaluation of canine epidermis and keratinocytoids (keratinocytic organoids) by transmission electron microscopy

Veterinary Dermatology, EarlyView.
Background – Skin disease is a common complaint in veterinary medicine. Current models often use live animals. Epidermal organoids (keratinocytoids) are 3D miniature organs created in culture from single epidermal keratinocytes. These keratinocytoids can be used as an alternative to live animal studies to investigate epidermal structures and skin ...
Clinson C. Lui, Dominique J. Wiener, Katia R. Groch, Lauren W. Stranahan, Christina R. Heard, Aníbal G. Armién   +5 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Insulin signalling in granulosa cells [PDF]

, 2012
Polycystic ovary syndrome (PCOS) is characterised by hyperandrogenism and insulin resistance. Granulosa cells in PCOS demonstrate impaired insulin-induced glucose uptake and lactate accumulation, suggesting a post receptor, signalling pathway-specific impairment of insulin action.
openaire   +3 more sources

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

Experimental Physiology, EarlyView.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller, M. Erin Moir, Brandon G. Fico   +2 more
wiley   +1 more source

Granulosa cell insight: unraveling the potential of menstrual blood-derived stem cells and their exosomes on mitochondrial mechanisms in polycystic ovary syndrome (PCOS)

Journal of Ovarian Research
Background Polycystic ovary syndrome (PCOS) presents a significant challenge in women’s reproductive health, characterized by disrupted folliculogenesis and ovulatory dysfunction.
Mahna Mansoori, Somayeh Solhjoo, Maria Grazia Palmerini, Seyed Noureddin Nematollahi-Mahani, Massood Ezzatabadipour   +4 more
doaj   +1 more source