Results 81 to 90 of about 10,360,699 (193)

FSH Regulates IGF-2 Expression in Human Granulosa Cells in an AKT-Dependent Manner.

Journal of Clinical Endocrinology and Metabolism, 2015
CONTEXT IGF-2 is highly expressed in the granulosa cells of human dominant ovarian follicles; however, little is known about the regulation of the IGF-2 gene or the interaction of IGF-2 and FSH during follicle development.
Sarah C. Baumgarten, S. Convissar, A. M. Zamah, M. A. Fierro, N. Winston, B. Scoccia, C. Stocco   +6 more
semanticscholar   +1 more source

Revealing the Impact of Mono(2‐ethylhexyl) Phthalate (MEHP) on Prostate Cancer Based on Network Toxicology and Molecular Docking Approaches

Journal of Applied Toxicology, EarlyView.
ABSTRACT Mono(2‐ethylhexyl) phthalate (MEHP) is a ubiquitous environmental contaminant and endocrine‐disrupting chemical (EDC), identified as a potential carcinogen. Emerging studies have begun to elucidate the impact of MEHP on prostate cancer (PCa), yet its pathogenic effects and the underlying molecular mechanisms remain unclear. This study seeks to
Chenyu Liang, Weicheng Tian, Hengxi Zeng, Ziyang Xia, Zijie Luo, Yue Zhuo, Minlian Pan, Kangbu Wu, Siyu Xiong, Xuejing Lin, Xinchun Li, Jiaxi Yu   +11 more
wiley   +1 more source

Study on the relationship between expression patterns of cocaine-and amphetamine regulated transcript and hormones secretion in porcine ovarian follicles

Biological Research, 2018
Background Cocaine-and amphetamine regulated transcript (CART) is an endogenous neuropeptide, which is widespread in animals, plays a key role in regulation of follicular atresia in cattle and sheep.
Pengfei Li, Jinzhu Meng, Jiongjie Jing, Qingling Hao, Zhiwei Zhu, Jianbo Yao, Lihua Lyu   +6 more
doaj   +1 more source

Ionic currents in avian granulosa cells [PDF]

FEBS Letters, 1988
Transmembrane ionic currents have been recorded in single granulosa cells from the laying hen using the whole‐cell patch‐clamp technique. Under voltage‐clamp conditions, depolarizing voltage steps evoked currents composed of a fast inactivating inward component and a delayed outward component. The former was activated at voltages more positive than −50
Schwartz, J., Mealing, Geoffrey, Asem, E., Whitfield, James, Tsang, B.   +4 more
openaire   +4 more sources

Functional microarray analysis of differentially expressed genes in granulosa cells from women with polycystic ovary syndrome related to MAPK/ERK signaling

Scientific Reports, 2015
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Although its aetiology and pathogenesis remain unclear, recent studies suggest that the dysfunction of granulosa cells may partly be responsible.
Chen‐Wei Lan, Mei-Jou Chen, K. Tai, Danny Cw Yu, Yu-Chieh Yang, Pey-shynan Jan, Yu‐Shih Yang, Hsin‐Fu Chen, H. Ho   +8 more
semanticscholar   +1 more source

Reproductive adverse events in patients with non‐Hodgkin lymphoma treated with chemotherapeutic regimens including cyclophosphamide, doxorubicin, vincristine, prednisone or CHOP with rituximab: A systematic review and meta‐analysis

Pediatric Discovery, EarlyView.
The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R‐CHOP) is the first‐line treatment for non‐Hodgkin lymphoma (NHL). Nine articles involving 331 patients were included in the meta‐analysis, the pooled proportion of reproductive adverse events was 22.3% (95% CI 11.4%–33.2%; p < 0.001). The findings
Rong Han, Jie Zhao, Chengjun Yu, Ling Wang, Long Chen, Yang Hu, Shengde Wu   +6 more
wiley   +1 more source

Transcriptome profiling of granulosa cells of bovine ovarian follicles during growth from small to large antral sizes

BMC Genomics, 2014
BackgroundAt later stages of folliculogenesis, the mammalian ovarian follicle contains layers of epithelial granulosa cells surrounding an antral cavity.
N. Hatzirodos, H. Irving-Rodgers, K. Hummitzsch, M. Harland, Stephanie E Morris, R. Rodgers   +5 more
semanticscholar   +1 more source

Comparative Analysis of the Progesterone Receptor Interactome in the Human Ovarian Granulosa Cell Line KGN and Other Female Reproductive Cells

PROTEOMICS, EarlyView.
ABSTRACT The nuclear steroid hormone receptor progesterone receptor (PGR) is expressed in granulosa cells in the ovarian follicle in a tightly regulated pattern in response to the surge of luteinizing hormone (LH) that stimulates ovulation. PGR plays a critical role in mediating ovulation in response to LH, however, the mechanism for this is still ...
Natalie J. Foot, Doan T. Dinh, Samantha J. Emery‐Corbin, Jumana M. Yousef, Laura F. Dagley, Darryl L. Russell   +5 more
wiley   +1 more source

Bisphenol A Induces Neuronal Apoptosis and Oxidative Stress Through TRPV4 Channel Signaling Pathways: Protective Role of Alpha‐Lipoic Acid

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), an environmental toxin, exerts adverse effects by increasing mitochondrial (mROS) and intracellular (iROS) reactive oxygen species, apoptosis, and Ca2+ influx in neurological diseases. However, antioxidants can mitigate these detrimental effects. This study aimed to investigate the protective role of antioxidant alpha‐lipoic
Ramazan Çinar, Mustafa Nazıroğlu
wiley   +1 more source

Follicle-stimulating hormone is expressed in ovarian follicles of chickens and promotes ovarian granulosa cell proliferation

Journal of Integrative Agriculture, 2021
Follicle-stimulating hormone (FSH), an important hypothalamic-pituitary-gonadal axis (HPG) hormone, is secreted by the pituitary gland. This study confirms that FSH is expressed in chicken follicles at different stages, and positive FSHβ mRNA signals ...
Yu-lin BI, Shu-yan YANG, Hai-yan WANG, Guo-bin CHANG, Guo-hong CHEN   +4 more
doaj