Results 161 to 170 of about 78,129 (305)

Granzyme B (GrB; GZMB) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

A novel diagnostic serum protein signature for pediatric inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Diagnostic delay is common in pediatric inflammatory bowel disease (PIBD), and fecal calprotectin (FCP) is often limited by challenges with sample collection. Therefore, we aimed to identify and validate a blood‐based diagnostic protein signature of PIBD.
Charlotte Bache‐Wiig Mathisen, Niklas Nyström, Igor Bazov, Ove Øyås, Manuela Zucknick, Svend Andersen, Christine Olbjørn, Gøri Perminow, Vendel A. Kristensen, Randi Opheim, Mauro D'Amato, Marie Carlson, Charlotte R. H. Hedin, Åsa V. Keita, Carl Mårten Lindqvist, Maria K. Magnusson, Samira Salihovic, Johan D. Söderholm, Lena Öhman, Robert Kruse, Dirk Repsilber, Jonas Halfvarson, Marte Lie Høivik   +22 more
wiley   +1 more source

The pro-tumorigenic roles of granzyme B: mechanisms and therapeutic implications. [PDF]

Front Immunol
Zhang Y, Huang H, Xie L, Li C, Zhou X.
europepmc   +1 more source

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, EarlyView.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

The application and prospect of granzyme B-targeted PET imaging in cancer immunotherapy. [PDF]

J Transl Med
Tong X, Jiang Y, Bi N.
europepmc   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Granzyme B from mast cells contributes to choroidal neovascularization in a model of wet age-related macular degeneration. [PDF]

Front Immunol
Uppal M, Hosseini A, Bilal K, Tan N, Ai Z, Khan W, Samad I, Gill G, Yoo HS, Chakravarthy H, Kuo CH, Xi J, Granville DJ, Matsubara JA.   +13 more
europepmc   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

The role of Janus kinase signaling in graft-versus-host disease and graft versus leukemia [PDF]

, 2018
Choi, Jaebok, DiPersio, John F, Schroeder, Mark A, Staser, Karl   +3 more
core   +2 more sources

Granzyme B-Targeting Quenched Activity-Based Probes for Assessing Tumor Response to Immunotherapy. [PDF]

J Am Chem Soc
Kazim M, Ganguly A, Malespini SM, Thang L, Patel NL, Kim C, Thakur K, Kalen JD, Calcagno C, Difilippantonio S, Yoo E.   +10 more
europepmc   +1 more source