Results 91 to 100 of about 54,390 (278)
The Italian Ministry of Agriculture funded in 2009 the “ARNADIA” Project, aimed at producing validated reference diagnostic protocols for the control and monitoring of plant pathogens of phytosanitary interest and, among them, grapevine viruses. In this
F. Faggioli +26 more
doaj +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Grapevine yield and wine quality in ancient Spanish Pyrenean vineyards: Influence of climatic and physiographic parameters [PDF]
Climate, edaphic, and physiographic parameters influence wine quality. In this study, we evaluated if climate and sediment connectivity had an effect on the grapevine yield (GY) and wine quality of three ancient (more than 100 years old) vineyards, with \
Donadel, Renate +7 more
core +2 more sources
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Functional characterisation of cuticle-related grapevine genes [PDF]
The epidermal layer of aerial plant tissues is covered by a hydrophobic structure known as the cuticle. This cuticular layer plays a major role in protecting the plant against abiotic and biotic stress factors, namely water loss and pathogen infection,
Vittani, L. +6 more
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
An Examination of Student Disengagement and Rengagement from an Alternative High School
Each year, 20% of U.S. students drop out of high school (Balfanz, Bridgeland, Bruce, & Fox, 2013). There is an abundance of research on student behaviors from researchers who explored the process of student disengagement from school (Bowers, Sprott ...
Marina Escamilla Flores +1 more
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

