Results 151 to 160 of about 1,094,918 (249)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia   +4 more
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

open access: yesExploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma   +13 more
wiley   +1 more source

First Report and Prevalence of Grapevine fleck virus in Grapevines (Vitis vinifera) in Canada

open access: yesPlant Disease, 2016
S. Poojari   +6 more
openaire   +1 more source

Grapevine Leafroll-Associated Virus 3 Replication in Grapevine Hosts Changes through the Dormancy Stage. [PDF]

open access: yesPlants (Basel), 2022
Čarija M   +5 more
europepmc   +1 more source

A mild strain of Grapevine leafroll-associated virus 3 is present in desirable clones of Crimson seedless table grapes in Western Australia

open access: yes, 2009
Also cited as: Le Progrès Agricole et Viticole, Hors Serie - Special Congrès ICVG; XVI Extended abstract published Conference proceedings / Elisabeth Boudon-Padieu (ed.): pp.237-238We have obtained superior clones of Crimson Seedless (CS) table grapes in
Randles, J., Habili, N., Cameron, I.
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