Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Pioneering plant virology research for a healthier future: a summary of the 2025 American Society for Virology (ASV) Plant Virology Satellite Symposium. [PDF]
Whitfield AE +7 more
europepmc +1 more source
Effect of In Vitro Culture of Long Shoot Tip on Variant Structure and Titer of Grapevine Viruses. [PDF]
Hu G, Dong Y, Zhang Z, Fan X, Ren F.
europepmc +1 more source
The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia +4 more
wiley +1 more source
Genome characterization of prunus maculavirus 1 (PrMcV-1), a novel member of the genus maculavirus identified in prunus spp. [PDF]
Abou Kubaa R +4 more
europepmc +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
First Report and Prevalence of Grapevine fleck virus in Grapevines (Vitis vinifera) in Canada
S. Poojari +6 more
openaire +1 more source
Limitations of Single Prediction Tools in miRNA Profiling of Grapevine Viral Coinfection. [PDF]
Jamnik K +4 more
europepmc +1 more source
Grapevine Leafroll-Associated Virus 3 Replication in Grapevine Hosts Changes through the Dormancy Stage. [PDF]
Čarija M +5 more
europepmc +1 more source
Also cited as: Le Progrès Agricole et Viticole, Hors Serie - Special Congrès ICVG; XVI Extended abstract published Conference proceedings / Elisabeth Boudon-Padieu (ed.): pp.237-238We have obtained superior clones of Crimson Seedless (CS) table grapes in
Randles, J., Habili, N., Cameron, I.
core

