Results 51 to 60 of about 1,094,918 (249)
Phytobiomes Journal, 2021 Grapevines are frequently infected by multiple viruses. Our previous study showed that Norton grapevine (Vitis aestivalis) is resistant to grapevine vein clearing virus (GVCV), a DNA virus in the family Caulimoviridae.
Susanne Howard +3 more
doaj +1 more source
Studies on \u27\u27corky rugose wood\u27\u27 of grapevine and on the diagnosis of grapevine virus B [PDF]
, 2015 Vines affected by corky rugose wood (CRW), a field syndrome characterized by pronounced cork production by the scion of several grapevine varieties just above the graft union, contain a number of filamentous and isometric phloem-limited viruses, such as ...
Boscia, D. +6 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
METODE DE ASANARE A PROTOCLONELOR DE VIȚĂ-DE-VIE ÎN PROCESUL DE SELECȚIE FITOSANITARĂ
Agricultural Science, 2023 This study addresses the use of hot water therapy, hot air therapy, and in vitro culture as additional techniques for eliminating viruses during the phytosanitary selection process of grapevines, aiming to produce healthy plants free from infectious ...
Marcela DUBCEAC
doaj +1 more source
, 2023 Grapevine Pinot gris virus (GPGV) was discovered in Trentino, Italy, where it was associated with symptoms of chlorotic mottling and leaf deformation (GLMD) (Giampetruzzi 2012).
Nicoletta Contaldo +5 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Uncovering Northeast Portugal grapevine\u27s varietal legacy [PDF]
, 2019 Northeast Portugal comprises the wine denominations "Douro" and "Trás-os-Montes". There are more than one hundred grapevine cultivars registered suitable for wine production in these regions (ministerial-orders number 1204/2006 and 383/2017), however ...
Donadel, Renate +4 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source