Results 111 to 120 of about 2,125,479 (331)
On the beta-number of linear forests with an even number of components
The beta-number of a graph is the smallest positive integer for which there exists an injective function such that each is labeled and the resulting set of edge labels is for some positive integer . The beta-number of is , otherwise.
Rikio Ichishima, Akito Oshima
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Distance antimagic labeling of circulant graphs
A distance antimagic labeling of graph $ G = (V, E) $ of order $ n $ is a bijection $ f:V(G)\rightarrow \{1, 2, \ldots, n\} $ with the property that any two distinct vertices $ x $ and $ y $ satisfy $ \omega(x)\ne\omega(y) $, where $ \omega(x) $ denotes ...
Syafrizal Sy +4 more
doaj +1 more source
Relations between the distinguishing number and some other graph parameters [PDF]
A distinguishing coloring of a simple graph $G$ is a vertex coloring of $G$ which is preserved only by the identity automorphism of $G$. In other words, this coloring ``breaks'' all symmetries of $G$.
Bahman Ahmadi +1 more
doaj +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

