Results 131 to 140 of about 2,536,304 (342)

An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region

open access: yesBMJ Global Health, 2022
Cristina Barroso Hofer   +19 more
doaj   +1 more source

Applying Graphical Design Techniques to Graph Visualisation [PDF]

open access: yes, 2005
This paper contains details of new criteria for graph layout, based on the concepts used in graphical design. Current graph layout criteria have been shown to be effective in measuring the quality of a graph layout, but they are ad-hoc and often miss ...
Rodgers, Peter, Taylor, Martyn
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Action planning for graph transition systems [PDF]

open access: yes, 2005
Graphs are suitable modeling formalisms for software and hardware systems involving aspects such as communication, object orientation, concurrency, mobility and distribution.
Lluch-Lafuente, Alberto   +5 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Heuristic Search for the Analysis of Graph Transition Systems [PDF]

open access: yes, 2006
Graphs are suitable modeling formalisms for software and hardware systems involving aspects such as communication, object orientation, concurrency, mobility and distribution.
Lluch-Lafuente, Alberto   +5 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Tits alternatives for graph products

open access: yes, 2015
We discuss various types of Tits Alternative for subgroups of graph products of groups, and prove that, under some natural conditions, a graph product of groups satisfies a given form of Tits Alternative if and only if each vertex group satisfies this ...
Antolin, Yago, Minasyan, Ashot
core   +1 more source

The t-Pebbling Number of Jahangir Graph [PDF]

open access: yes, 2012
Given a configuration of pebbles on the vertices of a connected graph G, a pebbling move (or pebbling step) is defined as the removal of two pebbles from a vertex and placing one pebble on an adjacent vertex.
Samuel Jeyaseelan, S.   +2 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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