Results 141 to 150 of about 2,536,304 (342)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
On the Beta-Number of Forests with Isomorphic Components
Discussiones Mathematicae Graph Theory, 2018 The beta-number, β (G), of a graph G is defined to be either the smallest positive integer n for which there exists an injective function f : V (G) → {0, 1, . . .
Ichishima Rikio +3 more
doaj +1 more source
Evolving Graphs by Graph Programming [PDF]
, 2018 Rule-based graph programming is a deep and rich topic. We present an approach to exploiting the power of graph programming as a representation and as an execution medium in an evolutionary algorithm (EGGP). We demonstrate this power in comparison with Cartesian Genetic Programming (CGP), showing that it is significantly more efficient in terms of ...
Timothy Atkinson 0001 +2 more
openaire +2 more sources
Graph Pattern Matching: From Intractable to Polynomial Time [PDF]
, 2010 Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong +5 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Relations between the distinguishing number and some other graph parameters [PDF]
ریاضی و جامعهA distinguishing coloring of a simple graph $G$ is a vertex coloring of $G$ which is preserved only by the identity automorphism of $G$. In other words, this coloring ``breaks'' all symmetries of $G$.
Bahman Ahmadi +1 more
doaj +1 more source
Distributed Graph Simulation: Impossibility and Possibility [PDF]
, 2014 This paper studies fundamental problems for distributed graph simulation. Given a pattern query Q and a graph G that is fragmented and distributed, a graph simulation algorithm A is to compute the matches Q(G) of Q in G.
Wang, Xin +3 more
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Graph Drawing Techniques for Geographic Visualization [PDF]
, 2004 Geovisualizers often need to represent data that consists of items related together. Such data sets can be abstracted to a mathematical structure, the graph.
Rodgers, Peter
core
The complexity of two graph orientation problems [PDF]
, 2012 This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 ElsevierWe consider two orientation problems in a graph, namely the minimization of the sum of all the shortest path ...
Noble, Steven D. +7 more
core +1 more source