Results 121 to 130 of about 3,533,009 (320)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

On covers of graphs by Cayley graphs [PDF]

open access: yesEuropean Journal of Combinatorics, 2017
We prove that every vertex transitive, planar, 1-ended, graph covers every graph whose balls of radius r are isomorphic to the ball of radius r in G for a sufficiently large r. We ask whether this is a general property of finitely presented Cayley graphs, as well as further related questions.
openaire   +3 more sources

On the beta-number of linear forests with an even number of components

open access: yesAKCE International Journal of Graphs and Combinatorics, 2018
The beta-number of a graph is the smallest positive integer for which there exists an injective function such that each is labeled and the resulting set of edge labels is for some positive integer . The beta-number of is , otherwise.
Rikio Ichishima, Akito Oshima
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Distance antimagic labeling of circulant graphs

open access: yesAIMS Mathematics
A distance antimagic labeling of graph $ G = (V, E) $ of order $ n $ is a bijection $ f:V(G)\rightarrow \{1, 2, \ldots, n\} $ with the property that any two distinct vertices $ x $ and $ y $ satisfy $ \omega(x)\ne\omega(y) $, where $ \omega(x) $ denotes ...
Syafrizal Sy   +4 more
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

A root graph that is locally the line graph of the Petersen graph

open access: yesDiscrete Mathematics, 2003
The authors construct a root graph on \(192\) vertices that is locally the line graph of the Petersen graph and they show that this graph is the unique root graph with \(\mu = 2\) that is locally the line graph of the Petersen graph (\(\mu = 2\) means that every two vertices at distance two have precisely two common neighbours).
Andries E. Brouwer   +2 more
openaire   +3 more sources

Random Graphs [PDF]

open access: bronze, 1959
E. N. Gilbert
openalex   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

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