Results 121 to 130 of about 2,125,479 (331)
Spectrum of prism graph and relation with network related quantities
Ali Raza +4 more
openalex +1 more source
Let \(G= (V,E)\) be a finite simple graph with \(n\geq 2\) vertices. \(G\) is called a concordance graph if the number of its induced three-vertex one-edged subgraphs equals the number of its induced three-vertex two-edged subgraphs, the class of these graphs be denoted by \({\mathfrak C}\).
Fishburn, Peter, Monjardet, Bernard
openaire +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
GREG: A Global Level Relation Extraction with Knowledge Graph Embedding [PDF]
Kuekyeng Kim +3 more
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Graph Neural Networks: A Review of Methods and Applications [PDF]
Jie Zhou +5 more
semanticscholar +1 more source
Rainbow Matchings in $r$-Partite $r$-Graphs [PDF]
Ron Aharoni, Eli Berger
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source

