Results 121 to 130 of about 3,533,009 (320)
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
On covers of graphs by Cayley graphs [PDF]
We prove that every vertex transitive, planar, 1-ended, graph covers every graph whose balls of radius r are isomorphic to the ball of radius r in G for a sufficiently large r. We ask whether this is a general property of finitely presented Cayley graphs, as well as further related questions.
openaire +3 more sources
On the beta-number of linear forests with an even number of components
The beta-number of a graph is the smallest positive integer for which there exists an injective function such that each is labeled and the resulting set of edge labels is for some positive integer . The beta-number of is , otherwise.
Rikio Ichishima, Akito Oshima
doaj +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
Distance antimagic labeling of circulant graphs
A distance antimagic labeling of graph $ G = (V, E) $ of order $ n $ is a bijection $ f:V(G)\rightarrow \{1, 2, \ldots, n\} $ with the property that any two distinct vertices $ x $ and $ y $ satisfy $ \omega(x)\ne\omega(y) $, where $ \omega(x) $ denotes ...
Syafrizal Sy +4 more
doaj +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
A root graph that is locally the line graph of the Petersen graph
The authors construct a root graph on \(192\) vertices that is locally the line graph of the Petersen graph and they show that this graph is the unique root graph with \(\mu = 2\) that is locally the line graph of the Petersen graph (\(\mu = 2\) means that every two vertices at distance two have precisely two common neighbours).
Andries E. Brouwer+2 more
openaire +3 more sources
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef+10 more
wiley +1 more source