Results 121 to 130 of about 5,338,929 (295)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

FGDB: a comprehensive graph database of ligand fragments from the Protein Data Bank. [PDF]

Database (Oxford), 2022
Toti D, Macari G, Barbierato E, Polticelli F.   +3 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

System of complex data analysis of thematic sites ISCAD IS

Informatika
Objectives. Currently, the main source of information is the Internet. The huge amount of information available on the Internet makes it urgent to comprehensively analyze data from open Internet sources.The goal of this work is to create a multi-purpose,
I. I. Piletski, M. P. Batura, N. A. Volоrоva, P. A. Zorko, A. O. Kulevich   +4 more
doaj   +1 more source

Graph Locality Prefetcher for Graph Database [PDF]

, 2016
This work presents a hardware prefetcher to improve the performance of accessing graph data representing large and complex networks. We represent complex networks as graphs, and queries amount to traversals on the graph.
Yin, Zhuoran
core  

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Review of the Application of Graph Database and Graph Computing in Power System Dispatch and Operation

Zhongguo dianli
As the widespread integration of new energy and interconnection of large power grids, the operation modes of power systems are undergoing transformations, which leads to a fast surge in data volumes and higher demands for real-time information processing,
Pei ZHANG, Majing YANG, Fang ZHANG, Hua XIE, Guangyi LIU, Wenyun LI, Xuegang LU, Zhenyi WANG, Suwei ZHAI   +8 more
doaj   +1 more source

Wheat Panache: A pangenome graph database representing presence-absence variation across sixteen bread wheat genomes. [PDF]

Plant Genome, 2022
Bayer PE, Petereit J, Durant É, Monat C, Rouard M, Hu H, Chapman B, Li C, Cheng S, Batley J, Edwards D.   +10 more
europepmc   +1 more source

Attack Graph to Graph Database

IOSR Journal of Computer Engineering, 2014
Databases are an integral part of almost any computing system today, and users heavily rely on the services they provide. When we interact with a computing system, we expect that any data be stored for future use, that the data is able to be looked up quickly, and that we can perform complex queries against the data stored in the database.
openaire   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source