Results 131 to 140 of about 3,576,657 (341)

Graph4Med: a web application and a graph database for visualizing and analyzing medical databases. [PDF]

open access: yesBMC Bioinformatics, 2022
Schäfer J   +4 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Graph-Based Automation of Threat Analysis and Risk Assessment for Automotive Security

open access: yesInformation
The proliferation of cyber–physical systems in modern vehicles, characterized by densely interconnected Electronic Control Units (ECUs) and heterogeneous communication networks, has significantly expanded the automotive attack surface. Traditional Threat
Mera Nizam-Edden Saulaiman   +2 more
doaj   +1 more source

Improving the Computational Performance of Ontology-Based Classification Using Graph Databases

open access: yesRemote Sensing, 2015
The increasing availability of very high-resolution remote sensing imagery (i.e., from satellites, airborne laser scanning, or aerial photography) represents both a blessing and a curse for researchers.
Thomas J. Lampoltshammer   +1 more
doaj   +1 more source

Converting relational to graph databases

open access: yes, 2013
"Graph Database Management Systems provide an effective and efficient solution to data storage in current scenarios where data are more and more connected, graph models are widely used, and systems need to scale to large data sets. In this framework, the
DE VIRGILIO, ROBERTO   +5 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search. [PDF]

open access: yesJ Chem Inf Model, 2023
Wills S   +8 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Home - About - Disclaimer - Privacy