Results 91 to 100 of about 845,204 (303)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Densely embedded graphs

open access: yesJournal of Combinatorial Theory, Series B, 1992
Let G be a graph embedded in a surface S. The face-width of the embedding is the minimum size \(| C\cap G|\) over all noncontractible cycles C in S. The face-width measures how densely a graph is embedded in a surface; equivalently, how well an embedded graph represents a surface.
openaire   +1 more source

Geometrical embeddings of graphs

open access: yesDiscrete Mathematics, 1989
First the paper considers generalized threshold graphs and gives a characterization of such graphs by a list of 11 forbidden induced subgraphs \((G_ 8\) being superfluous since it contains \(G_ 2\) as an induced subgraph). Then the scalar product dimension d(G) of a graph \(G=(V,E)\) is defined to be the minimum number d such that there exists a ...
Jan Reiterman   +2 more
openaire   +2 more sources

Graph Homomorphism Revisited for Graph Matching [PDF]

open access: yes, 2010
In a variety of emerging applications one needs to decide whether a graph G matches another Gp, i.e., whether G has a topological structure similar to that of Gp. The traditional notions of graph homomorphism and isomorphism often fall short of capturing
Li, Jianzhong   +4 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Algorithmic graph embeddings

open access: yesTheoretical Computer Science, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Graph Embeddings at Scale

open access: yesCoRR, 2019
Graph embedding is a popular algorithmic approach for creating vector representations for individual vertices in networks. Training these algorithms at scale is important for creating embeddings that can be used for classification, ranking, recommendation and other common applications in industry.
C. Bayan Bruss   +5 more
openaire   +3 more sources

Simultaneous Graph Embedding with Bends and Circular Arcs

open access: yes, 2007
We consider the problem of simultaneous embedding of planar graphs. We demonstrate how to simultaneously embed a path and an n-level planar graph and how to use radial embeddings for curvilinear simultaneous embeddings of a path and an outerplanar ...
Cappos, Justin   +3 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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