Results 41 to 50 of about 236,543 (259)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Certain Energies of Graphs for Dutch Windmill and Double-Wheel Graphs
Journal of Mathematics, 2022 Energy of a graph is defined as the sum of the absolute values of the eigenvalues of the adjacency matrix associated with the graph. In this research work, we find color energy, distance energy, Laplacian energy, and Seidel energy for the Dutch windmill ...
Jing Wu +4 more
doaj +1 more source
On the spectrum and energy of singular graphs [PDF]
AKCE International Journal of Graphs and Combinatorics, 2019 Energy of a graph is defined as the sum of the absolute values of the eigenvalues of the adjacency matrix of a graph and is denoted by . The graph with vertices is called nonhypoenergetic if and hypoenergetic if . Singular graphs are graphs with nullity . In this paper we study about nonhypoenergetic and hypoenergetic graphs among singular graphs.
T. K. Mathew Varkey, John K. Rajan
openaire +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Time-Dependent Lagrangian Energy Systems on Supermanifolds with Graph Bundles
Journal of Mathematics, 2021 The aim of this article is firstly to improve time-dependent Lagrangian energy equations using the super jet bundles on supermanifolds. Later, we adapted this study to the graph bundle.
Cansel Aycan, Simge Şimşek
doaj +1 more source
On the spectrum, energy and Laplacian energy of graphs with self-loops
Heliyon, 2023 The total energy of a conjugated molecule's π-electrons is a quantum-theoretical feature that has been known since the 1930s. It is determined using the Huckel tight-binding molecular orbital (HMO) method.
Ugasini Preetha P +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Investigation of the Main Energies of Picture Fuzzy Graph and its Applications
International Journal of Computational Intelligence Systems, 2022 Picture fuzzy graph, belonging to fuzzy graphs family, has good capabilities at times when we are faced with problems that cannot be expressed by fuzzy graphs and intuitionistic fuzzy graphs.
Xiaolong Shi +4 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source