Results 81 to 90 of about 802,028 (300)

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

open access: yesAdvanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky   +15 more
wiley   +1 more source

Phenotype Diversity Objectives for Graph Grammar Evolution

open access: yes, 2005
This paper explores theu se of phenotype diversity measu res as objectives in a graph grammar-based model of mu lti-objective graph evolu23 n.
Martin H. Luerssen   +1 more
core  

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li   +15 more
wiley   +1 more source

Reorganization in Multi-Agent Architectures: An Active Graph Grammar Approach

open access: yesBusiness Systems Research, 2013
Background: Organizational architecture is a holistic approach to design of humane organizations and studies an organization from five perspectives: structure, culture, processes, strategy and individuals.
Schatten Markus
doaj   +1 more source

A Bright Ratiometric Dipyrene Probe for Functional Imaging of Condensate Microenvironments in Living Cells

open access: yesAdvanced Science, EarlyView.
Ratiometric dipyrene imaging resolves monomer (M) and excimer (E) channels and computes pixel‐wise E/M maps within biomolecular condensates, yielding physicochemical fingerprints shaped by coupled polarity‐related solvation and microviscosity. These spatial fingerprints enable quantitative phenotyping of cellular states, exemplified by separation of ...
Koki Matsumoto   +20 more
wiley   +1 more source

TRANSLATING ERLANG STATE MACHINES TO UML USING TRIPLE GRAPH GRAMMARS

open access: yesStudia Universitatis Babes-Bolyai: Series Informatica, 2018
In this paper, we present a method that transforms event driven Erlang state machines into high-level state machine models represented in UML. We formalized the transformation system as a triple graph grammar, a special case of graph rewriting. We argue
Dániel LUKÁCS, Melinda TÓTH
doaj   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

open access: yesAdvanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin   +8 more
wiley   +1 more source

Learning non-confluent NLC graph grammar rules [PDF]

open access: yes, 2009
Grammar inference deals with determining (preferable simple) models/grammars consistent with a set of observations. There is a large body of research on grammar inference within the theory of formal languages.
Blockeel, Hendrik, Brijder, Robert
core  

Graph Grammar Engineering with PROGRES

open access: yes, 1995
Graph-like data structures and rule-based systems play an important role within many branches of computer science. Nevertheless, their symbiosis in the form of graph rewriting systems or graph grammars are not yet popular among software engineers.
Zündorf, Albert   +7 more
core   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

open access: yesAdvanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang   +13 more
wiley   +1 more source

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