Results 71 to 80 of about 168,763 (311)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Minimum Spanning Trees for Minor-Closed Graph Classes in Parallel [PDF]

open access: yes, 1997
For each minor-closed graph class we show that a simple variant of Boruvka's algorithm computes a MST for any input graph belonging to that class with linear costs.
Jens Gustedt, Gustedt, Jens
core   +1 more source

Forward-Propagation Approach for Generating Feasible and Minimum Test Case Suites From Cause-Effect Graph Specifications

open access: yesIEEE Access, 2022
Cause-effect graphs are a popular black-box testing technique. The most commonly used approach for generating test cases from cause-effect graph specifications uses backward-propagation of forced effect activations through the graph in order to get the ...
Ehlimana Krupalija   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A formula for all minors of the adjacency matrix and an application

open access: yesSpecial Matrices, 2014
We supply a combinatorial description of any minor of the adjacency matrix of a graph. This descriptionis then used to give a formula for the determinant and inverse of the adjacency matrix, A(G), of agraph G, whenever A(G) is invertible, where G is ...
Bapat R. B., Lal A. K., Pati S.
doaj   +1 more source

Co-regulation of metabolic genes is better explained by flux coupling than by network distance. [PDF]

open access: yesPLoS Computational Biology, 2008
To what extent can modes of gene regulation be explained by systems-level properties of metabolic networks? Prior studies on co-regulation of metabolic genes have mainly focused on graph-theoretical features of metabolic networks and demonstrated a ...
Richard A Notebaart   +3 more
doaj   +1 more source

Graph minors. XXI. Graphs with unique linkages

open access: yesJournal of Combinatorial Theory, Series B, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Neil Robertson 0001, Paul D. Seymour
openaire   +1 more source

On triangles in ‐minor free graphs [PDF]

open access: yesJournal of Graph Theory, 2017
AbstractWe study graphs where each edge that is incident to a vertex of small degree (of degree at most 7 and 9, respectively) belongs to many triangles (at least 4 and 5, respectively) and show that these graphs contain a complete graph (K6 and K7, respectively) as a minor. The second case settles a problem of Nevo.
Boris Albar, Daniel Gonçalves 0001
openaire   +1 more source

Explicit bounds for graph minors [PDF]

open access: yesJournal of Combinatorial Theory, Series B, 2018
24 pages, 0 ...
Geelen J., Huynh T., Bruce Richter R.
openaire   +5 more sources

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