Results 51 to 60 of about 175,549 (222)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Recent Advances in Graph Partitioning

, 2015
We survey recent trends in practical algorithms for balanced graph partitioning together with applications and future research ...
A Buluç, A Felner, A George, A Lisser, A Pothen, A Trifunović, AB Kahng, AE Feldmann, AH Land, AJ Soper, B Brandfass, B Hendrickson, B Hendrickson, B Hendrickson, B Junker, B Monien, B Peng, BW Kernighan, C Aykanat, C Chevalier, C Chevalier, C Farhat, C Lanczos, C Walshaw, C Walshaw, C Walshaw, C Walshaw, C Walshaw, C Walshaw, CE Bichot, CE Ferreira, D Delling, D Delling, D Delling, D Drake, D Luxen, D Ron, D Ron, D Wagner, DA Papa, DE Drake Vinkemeier, E Jeannot, E Rolland, F Comellas, F Glover, F Glover, F Pellegrini, F Pellegrini, F Pellegrini, F Schulz, FT Leighton, G Even, G Karypis, G Karypis, G Karypis, G Zumbusch, H Li, H Meyerhenke, H Meyerhenke, H Meyerhenke, H Meyerhenke, H Meyerhenke, HD Simon, HD Simon, I Moulitsas, I Safro, I Safro, J Chen, J Cong, J Fietz, J Hromkovič, J Hungershöfer, J Maue, J Maue, J Shalf, JR Gilbert, K Andreev, K Lang, K Schloegel, K Schloegel, K Schloegel, KS Camilus, L Brunetta, L Grady, L Lovász, LA Sanchis, LR Ford, M Armbruster, M Bader, M Birn, M Fiedler, M Jerrum, M Newman, M Sellmann, M Zhou, MR Garey, N Sensen, O Goldschmidt, P Chardaire, P Galinier, P Korosec, P Sanders, P Sanders, R Diekmann, R Diekmann, R Glantz, R Preis, RD Williams, S Arora, S Huang, S Lafon, S Lloyd, S Pettie, SE Karisch, SY Chan, T Bui, T Kieritz, U Benlic, U Benlic, U Feige, V Osipov, WE Donath, WE Donath, WW Hager, WW Hager, X Sui, Y Low, YM Kim, Ü Çatalyürek   +128 more
core   +1 more source

On partitions of graphs into trees

Discrete Mathematics, 1978
AbstractWe consider the minimum number ⊤(G) of subsets into which the edge set E(G) of a graph G can be partitioned so that each subset forms a tree. It is shown that for any connected G with n vertices, we always have τ(G)⩽⌈12n⌉.
openaire   +2 more sources

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Toward a human‐centric co‐design methodology for AI detection of differences between planned and delivered dose in radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Many artificial intelligence (AI) solutions have been proposed to enhance the radiotherapy (RT) workflow, but limited applications have been implemented to date, suggesting an implementation gap. One contributing factor to this gap is a misalignment between AI systems and their users.
Luca M. Heising, Frank Verhaegen, Stefan G. Scheib, Maria J. G. Jacobs, Carol X. J. Ou, Viola Mottarella, Yin‐Ho Chong, Mariangela Zamburlini, Sebastiaan M. J. J. G. Nijsten, Ans Swinnen, Michel Öllers, Cecile J. A. Wolfs   +11 more
wiley   +1 more source

Partitioning graphs into complete and empty graphs

Discrete Mathematics, 2009
AbstractGiven integers j and k and a graph G, we consider partitions of the vertex set of G into j+k parts where j of these parts induce empty graphs and the remaining k induce cliques. If such a partition exists, we say G is a (j,k)-graph. For a fixed j and k we consider the maximum order n where every graph of order n is a (j,k)-graph.
John Gimbel, Tınaz Ekim
openaire   +2 more sources

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee, Subha Perni, Kelly J. Perrin, Kevin E. Casey, Alexandra O. Leone, Callistus M. Nguyen, Laurence E. Court, He Wang, Xin Wang, Eun Young Han   +9 more
wiley   +1 more source

High-Quality Shared-Memory Graph Partitioning

, 2018
Partitioning graphs into blocks of roughly equal size such that few edges run between blocks is a frequently needed operation in processing graphs. Recently, size, variety, and structural complexity of these networks has grown dramatically. Unfortunately,
A Buluç, CL Staudt, H Meyerhenke, Henning Meyerhenke, P Sanders   +4 more
core   +1 more source

Surface dose analysis and dosimetric comparison of Halcyon versus Truebeam in breast cancer radiotherapy: An OSL dosimetry study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar, Kudret Akçay, Esra Serin, Dursun Eşitmez, Mehmet Sıddık Cebe, Navid Kheradmand, Ömer Yazıcı, Dilek Ünal, Evrim Metcalfe   +8 more
wiley   +1 more source