Results 71 to 80 of about 36,227 (305)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A graph \(G\) admits a tree-partition of width \(k\) if its vertex set can be partitioned into sets of size at most \(k\) so that the graph obtained by identifying the vertices in each set of the partition, and then deleting loops and parallel edges, is a forest. If no such \(k\) exist, the width is set to be infinite.
Guoli Ding, Bogdan Oporowski
openaire +2 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Abstract A set of vertices S of a graph G is convex if all vertices of every geodesic between two of its vertices are in S . We say that G is k-convex if V ( G ) can be partitioned into k convex sets. The convex partition number of G is the least k ⩾ 2 for which G is k -convex.
Danilo Artigas +2 more
openaire +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bill Jackson, Tibor Jordán
openaire +2 more sources
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
A modified multilevel k-way partitioning algorithm for trip-based road networks [PDF]
In today’s world, the traffic volume on urban road networks is multiplying rapidly due to the heavy usage of vehicles and mobility on demand services. Migration of people towards urban areas result in increasing size and complexity of urban road networks.
Withanage C +5 more
doaj +1 more source
Partitions of Graphs into Trees [PDF]
In this paper, we study the k-tree partition problem which is a partition of the set of edges of a graph into k edge-disjoint trees. This problem occurs at several places with applications e.g. in network reliability and graph theory. In graph drawing there is the still unbeaten (n - 2) ×(n - 2) area planar straight line drawing of maximal planar ...
Therese Biedl, Franz-Josef Brandenburg
openaire +1 more source

