Results 101 to 110 of about 945,213 (292)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Signed Graph Equation [PDF]

open access: yes, 2009
For standard terminology and notion in graph theory we refer the reader to Harary [7]; the non-standard will be given in this paper as and when required.
Reddy, P. Siva Kota   +3 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

SOME CHEMICAL TOPOLOGICAL INDICES FOR THE COPRIME GRAPH OF THE INTEGERS MODULO GROUP

open access: yesBarekeng
This paper delves into the exploration of the coprime graph of a finite group G, a graph with vertices representing all group elements. Vertices x and y are considered adjacent in ΓG if their orders are relatively prime.
Gustina Elfiyanti   +4 more
doaj   +1 more source

A concrete realization of the slow-fast alternative for a semilinear heat equation with homogeneous Neumann boundary conditions

open access: yesAdvances in Nonlinear Analysis, 2018
We investigate the asymptotic behavior of solutions to a semilinear heat equation with homogeneous Neumann boundary conditions. It was recently shown that the nontrivial kernel of the linear part leads to the coexistence of fast solutions decaying to 0 ...
Ghisi Marina   +2 more
doaj   +1 more source

On Fundamental Solution for Autonomous Linear Retarded Functional Differential Equations

open access: yesMathematics, 2020
This document focuses attention on the fundamental solution of an autonomous linear retarded functional differential equation (RFDE) along with its supporting cast of actors: kernel matrix, characteristic matrix, resolvent matrix; and the Laplace ...
Clement McCalla
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Randić spectrum of the weakly zero-divisor graph of the ring ℤn

open access: yesAKCE International Journal of Graphs and Combinatorics
In this article, we find the Randić spectrum of the weakly zero-divisor graph of a finite commutative ring [Formula: see text] with identity [Formula: see text], denoted as [Formula: see text], where [Formula: see text] is taken as the ring of integers ...
Nadeem Ur Rehman   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Zagreb-Type Indices of the Fractal Graphs Based on Star Graphs

open access: yesAxioms
Zagreb-type indices are topological indices derived from the degrees of nodes. The first Zagreb index, the F-index, and the Y-index represent the sum of the squares, cubes, and fourth powers of all node degrees, respectively.
Xintian Jia, Wenjie Wang
doaj   +1 more source

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