Results 61 to 70 of about 144,663 (217)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Categorical constructions in graph theory

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1986
This paper presents some graph-theoretic questions from the viewpoint of the portion of category theory which has become common knowledge. In particular, the reader is encouraged to consider whether there is only one natural category of graphs and how ...
Richard T. Bumby, Dana May Latch
doaj   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Graph Theory Students’ Perceptions of Graph Isomorphism [PDF]

open access: yesIranian Journal of Educational Research
Objective: Graph isomorphism is a central topic in graph theory, yet students often struggle to grasp its underlying principles. This study aimed to explore students' perceptions of graph isomorphism and identify the conceptual metaphors they employ when
Ali Jafari   +2 more
doaj  

Time-varying Analysis of Brain Networks Based on High-order Dynamic Functional Connections in Mild Cognitive Impairment

open access: yesChinese Journal of Magnetic Resonance
Existing research commonly uses functional connectivity (FC) combined with graph theory analysis to accomplish the auxiliary diagnosis of mild cognitive impairment (MCI).
WANG Xia, WANG Yong, LAN Qing
doaj   +1 more source

Graph Theory of Tower Tasks

open access: yesBehavioural Neurology, 2012
The appropriate mathematical model for the problem space of tower transformation tasks is the state graph representing positions of discs or balls and their moves.
Andreas M. Hinz
doaj   +1 more source

Graph Theory; History, Applications, and, Vision [PDF]

open access: yesریاضی و جامعه
Graph theory is a leading theory in mathematics, which is used in many sciences. In this article, by stating the history of this, its expansion and development, we have mentioned the course of famous problems in graph theory.
Meysam Taheri Dehkordi
doaj   +1 more source

Application of graph theory in liver research: A review

open access: yesPortal Hypertension & Cirrhosis
Graph theory has emerged as a valuable tool in liver research, aiding in the assessment of complex interactions underlying liver diseases at different organizational levels.
Xumei Hu   +7 more
doaj   +1 more source

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