Results 61 to 70 of about 123,181 (264)

Graph Theory in the Analysis of Arithmophobia

open access: yesInternational Journal of Innovative Technology and Exploring Engineering, 2019
In this paper, Graph theoretical concepts are applied to analyze the reasons behind Arithmophobia commonly found among the students.Bull graph is used to epitomize Mild Arithmophobia which occurs when the preparation of students to face any test is deficient.Flower graph is used to represent Intense Arithmophobia.
A. Uma Maheswari*, A.S. Purnalakshimi
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Altered EEG Brain Networks in Patients with Acute Peripheral Herpes Zoster

open access: yesJournal of Pain Research, 2021
Yan Zhou,1– 3 Zhenqin Liu,4 Yuanmei Sun,5 Hao Zhang,1,3 Jianghai Ruan1,3 1Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, People’s Republic of China; 2Department of Neurology, Jianyang People’s Hospital ...
Zhou Y, Liu Z, Sun Y, Zhang H, Ruan J
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Distributed Load Flow Analysis Using Graph Theory

open access: yes, 2011
{"references": ["W.F Tinny and C.E. Hart, \"Power flow solution of the Newton Method\",\nIEEE Transactions, PAS-86, 1967, pp. 1449-1456.", "B. Scott and O. Alsac, \"Fast decoupled load flow\", IEEE Transactions,\nPAS-93, 1974, pp. 859-869.", "M.E. Baran and F.
D. P. Sharma   +3 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

On topological indices and entropy measures of beryllonitrene network via logarithmic regression model

open access: yesScientific Reports
Chemical graph theory, a subfield of graph theory, is used to investigate chemical substances and their characteristics. Chemical graph analysis sheds light on the connection, symmetry, and reactivity of molecules.
Guofeng Yu   +5 more
doaj   +1 more source

A cluster analysis based on graph theory

open access: yesVegetatio, 1974
A clustering method is presented that groups sample plots (stands or other units) together, based on their proximity in a multidimensional test space in which the axes represent the attributes (species) of the individuals (sample plots, etc.). The resulting dendrogram is used to make subjective judgements on the type and distinctiveness of the ...
Van Groenewoud, H., Ihm, P.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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