Results 81 to 90 of about 1,208,308 (285)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Regularity in Vague Intersection Graphs and Vague Line Graphs

Abstract and Applied Analysis, 2014
Fuzzy graph theory is commonly used in computer science applications, particularly in database theory, data mining, neural networks, expert systems, cluster analysis, control theory, and image capturing.
Muhammad Akram, Wieslaw A. Dudek, M. Murtaza Yousaf   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Asymptotics of classical spin networks

, 2011
A spin network is a cubic ribbon graph labeled by representations of $\mathrm{SU}(2)$. Spin networks are important in various areas of Mathematics (3-dimensional Quantum Topology), Physics (Angular Momentum, Classical and Quantum Gravity) and Chemistry ...
Biedenharn, Biedenharn, Bloch, Blumenthal, Carter, Dupuis, Garoufalidis, Grünberg, Kauffman, Kirillov, Miller, Moussouris, Olver, Penrose, Penrose, Ponzano, Roland van der Veen, Stavros Garoufalidis, Turaev, Westbury, Wigner   +20 more
core   +1 more source

Distributed Load Flow Analysis Using Graph Theory

, 2011
{"references": ["W.F Tinny and C.E. Hart, \"Power flow solution of the Newton Method\",\nIEEE Transactions, PAS-86, 1967, pp. 1449-1456.", "B. Scott and O. Alsac, \"Fast decoupled load flow\", IEEE Transactions,\nPAS-93, 1974, pp. 859-869.", "M.E. Baran and F.
D. P. Sharma, A. Chaturvedi, G.Purohit, R.Shivarudraswamy   +3 more
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

On topological indices and entropy measures of beryllonitrene network via logarithmic regression model

Scientific Reports
Chemical graph theory, a subfield of graph theory, is used to investigate chemical substances and their characteristics. Chemical graph analysis sheds light on the connection, symmetry, and reactivity of molecules.
Guofeng Yu, Muhammad Kamran Siddiqui, Mazhar Hussain, Nazir Hussain, Zohaib Saddique, Fikre Bogale Petros   +5 more
doaj   +1 more source

Disrupted Structural and Functional Networks and Their Correlation with Alertness in Right Temporal Lobe Epilepsy: A Graph Theory Study

Frontiers in Neurology, 2017
Previous studies have shown that temporal lobe epilepsy (TLE) involves abnormal structural or functional connectivity in specific brain areas. However, limited comprehensive studies have been conducted on TLE associated changes in the topological ...
Wenyu Jiang, Jianping Li, Xuemei Chen, Wei Ye, Jinou Zheng   +4 more
doaj   +1 more source

A cluster analysis based on graph theory

Vegetatio, 1974
A clustering method is presented that groups sample plots (stands or other units) together, based on their proximity in a multidimensional test space in which the axes represent the attributes (species) of the individuals (sample plots, etc.). The resulting dendrogram is used to make subjective judgements on the type and distinctiveness of the ...
Van Groenewoud, H., Ihm, P.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source