Results 61 to 70 of about 1,208,308 (285)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Markov Chain Methods For Analyzing Complex Transport Networks

, 2007
We have developed a steady state theory of complex transport networks used to model the flow of commodity, information, viruses, opinions, or traffic. Our approach is based on the use of the Markov chains defined on the graph representations of transport
A. Bjöner, A. Bjöner, A. Cardillo, B. Bollobás, B. Hillier, B. Hillier, B.T. Backus, D. Braess, D. Gross, D. Volchenkov, D. Volchenkov, F. Chung, F. Chung, F. Chung, G.L. Alexanderson, I. Farkas, I.J. Farkas, J.-L. Lagrange, K.A. Eriksen, L. Arnold, L. Lovász, L. Lovász, M. Loève, M. Rosvall, N. Alon, N. Aubry, N. Aubry, N. Biggs, P. Blanchard, P. Crucitti, Ph. Blanchard, S. Butler, S. Porta, S. Scellato, S.N. Dorogovtsev, Ya.G. Sinai   +35 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Small‐world network and neuroscience

Brain-X
Small‐world networks are of great significance in the field of neuroscience. As the universal nature of the human brain network, their heterogeneous pattern of change in patients with different diseases may satisfy the need for auxiliary objective ...
Yan‐Kun Han, Hai‐Jun Zhang, Yu‐Jing Chen, Chang Liu, Yu‐He Zhang, Zhan‐Jun Zhang, Run‐Ting Jing, Li Guo, Da Li, Wen‐Yue Chu, Wen‐Jun Wu, Kan Zhang, Long‐Biao Cui   +12 more
doaj   +1 more source

Cytoscape.js: a graph theory library for visualisation and analysis [PDF]

Bioinformatics, 2015
Abstract Summary: Cytoscape.js is an open-source JavaScript-based graph library. Its most common use case is as a visualization software component, so it can be used to render interactive graphs in a web browser.
Franz, Max, Lopes, Christian T., Huck, Gerardo, Dong, Yue, Sumer, Onur, Bader, Gary D.   +5 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Graph theory, irreducibility, and structural analysis of differential-algebraic equation systems [PDF]

, 2014
The $\Sigma$-method for structural analysis of a differential-algebraic equation (DAE) system produces offset vectors from which the sparsity pattern of a system Jacobian is derived.
Nedialkov, Nedialko S., Pryce, John D., Tan, Guangning   +2 more
core   +1 more source

Invertibility of graph translation and support of Laplacian Fiedler vectors

, 2017
The graph Laplacian operator is widely studied in spectral graph theory largely due to its importance in modern data analysis. Recently, the Fourier transform and other time-frequency operators have been defined on graphs using Laplacian eigenvalues and ...
Begué, Matthew, Okoudjou, Kasso A.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

行星轮系的图论模型及其应用

Jixie chuandong, 2008
Through analysis of the graph theory model,the conditions that the EGTs’ graph theory model must be met is summarized.On the basis of graph theory model presented in literature[1],a concept of module entity and basic loop in graph theory model is ...
史晓影, 陈良钰, 薛隆泉
doaj