Results 91 to 100 of about 1,279,869 (296)

Interactive Visualization of Graph Pyramids [PDF]

open access: yes, 2006
Graph or image pyramids can be used for hierarchical partitioning of images. One related application area is the automatical determination of landscapes in Landscape Ecology.
Andreas Kerren, Kerren, Andreas
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

An object-oriented design for graph visualization [PDF]

open access: yes, 2000
Many applications, from everyday file system browsers to visual programming tools, require the display of network and graph structures. The Graph Visualization Framework (GVF) is an architecture that supports the tasks common to most graph browsers and ...
Herman, Ivan   +4 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Visualize online collocation dictionary with force-directed graph [PDF]

open access: yes, 2012
For second-language learners, collocational knowledge is very important. Knowing collocational phrases allows learners to speak and write in their targeted language naturally and reduce dramatically side effect of their first language.
Pham, Bob
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Graph Visualization Tools: A Comparative Analysis

open access: yesJISR on Computing, 2015
Data visualization is becoming a necessity for big organizations as the social networking data is growing rapidly. It is becoming difficult to visualize data and perform complex comparisons.
Fariha Majeed, Saif-ur-Rahman
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

From Databases to Graph Visualization

open access: yes2010 14th International Conference Information Visualisation, 2010
The first step of any information visualization system is to enable end user to import their dataset into the system. However, non expert user are faced to the difficult task of choosing how their data should/could be transform to be used in these Infovis systems.
Gilbert, Frédéric, Auber, David
openaire   +4 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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